Treatment patterns and outcomes in goblet cell carcinoid tumors of the appendix
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Surgical Oncology"
DOI: 10.1002/jso.25723
Abstract: Goblet cell carcinoid (GCC) tumors of the appendix are a rare malignancy. We aim to examine the overall survival per stage and the relationship between different treatment modalities and outcomes for patients with GCC tumors… read more here.
Keywords: goblet cell; cell carcinoid; tumors appendix;
Gallic acid prevents 1, 2‐Dimethylhydrazine induced colon inflammation, toxicity, mucin depletion, and goblet cell disintegration
Sign Up to like & getrecommendations! Published in 2020 at "Environmental Toxicology"
DOI: 10.1002/tox.22900
Abstract: 1,2‐Dimethylhydrazine (DMH), an environmental toxicant specifically targets the colon. The present study was aimed to evaluate the efficacy of gallic acid (GA) against colon toxicity induced by DMH in Wistar rats. GA, a phenolic acid… read more here.
Keywords: cell disintegration; mucin depletion; inflammation; colon ... See more keywords
Atypical goblet cell hyperplasia occurs in CPAM 1, 2, and 3, and is a probable precursor lesion for childhood adenocarcinoma
Sign Up to like & getrecommendations! Published in 2019 at "Virchows Archiv"
DOI: 10.1007/s00428-019-02732-4
Abstract: Congenital pulmonary airway malformation (CPAM) is a developmental disorder. Types 1-2-3 are the more common ones. Atypical goblet cell hyperplasia (AGCH) in CPAM might be a precursor lesion for pulmonary adenocarcinomas. In nine out of… read more here.
Keywords: goblet cell; cpam; precursor lesion;
CDX-2 Expression in Esophageal Biopsies Without Goblet Cell Intestinal Metaplasia May Be Predictive of Barrett’s Esophagus
Sign Up to like & getrecommendations! Published in 2019 at "Digestive Diseases and Sciences"
DOI: 10.1007/s10620-019-05914-x
Abstract: Background CDX-2 is a nuclear homeobox transcription factor not normally expressed in esophageal and gastric epithelia, reported to highlight intestinal metaplasia (IM) in the esophagus. Pathological absence of goblet cells at initial screening via hematoxylin… read more here.
Keywords: intestinal metaplasia; barrett esophagus; goblet; cdx ... See more keywords
Adenocarcinoma Ex-goblet Cell Carcinoid of the Appendix: a Case Report and Overview of the Disease
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Gastrointestinal Cancer"
DOI: 10.1007/s12029-017-9926-9
Abstract: Goblet cell carcinoid (GCC) of the appendix is a rare disease with varying guidelines for histopathologic diagnosis and management. The disease is intriguing in terms of its pathologic features. Three subtypes have been described depending… read more here.
Keywords: goblet cell; cell carcinoid; disease;
Interleukin‐33 induces mucin gene expression and goblet cell hyperplasia in human nasal epithelial cells
Sign Up to like & getrecommendations! Published in 2017 at "Cytokine"
DOI: 10.1016/j.cyto.2016.10.010
Abstract: HighlightsIL‐33 was upregulated in nasal polyps of eosinophilic chronic rhinosinusitis.IL‐33 increase MUC5AC gene and MUC5AC protein in primary human nasal epithelial cell.IL‐33 induces goblet cell hyperplasia in primary human nasal epithelial cell. Abstract We investigated… read more here.
Keywords: nasal epithelial; human nasal; cell hyperplasia; goblet cell ... See more keywords
Appendiceal goblet cell carcinoid: common errors in staging and clinical interpretation with a proposal for an improved terminology.
Sign Up to like & getrecommendations! Published in 2017 at "Human pathology"
DOI: 10.1016/j.humpath.2017.05.012
Abstract: Goblet cell carcinoid (GCC) is staged and treated as adenocarcinoma (AC) and not as neuroendocrine tumor (NET) or neuroendocrine carcinoma. The term carcinoid may lead to incorrect interpretation as NET. The aim of the study… read more here.
Keywords: gcc; goblet cell; mixed gcc; staging clinical ... See more keywords
Loss of Mucosal p32/gC1qR/HABP1 Triggers Energy Deficiency and Impairs Goblet Cell Differentiation in Ulcerative Colitis
Sign Up to like & getrecommendations! Published in 2021 at "Cellular and Molecular Gastroenterology and Hepatology"
DOI: 10.1016/j.jcmgh.2021.01.017
Abstract: Background & Aims Cell differentiation in the colonic crypt is driven by a metabolic switch from glycolysis to mitochondrial oxidation. Mitochondrial and goblet cell dysfunction have been attributed to the pathology of ulcerative colitis (UC).… read more here.
Keywords: cell differentiation; energy; goblet; goblet cell ... See more keywords
The development of an in vitro 3D model of goblet cell hyperplasia using MUC5AC expression and repeated whole aerosol exposures.
Sign Up to like & getrecommendations! Published in 2021 at "Toxicology letters"
DOI: 10.1016/j.toxlet.2021.04.012
Abstract: Goblet cell hyperplasia and overproduction of airway mucin are characteristic features of the lung epithelium of smokers and COPD patients. Tobacco heating products (THPs) are a potentially less risky alternative to combustible cigarettes, and through… read more here.
Keywords: exposure; aerosol; whole aerosol; cell hyperplasia ... See more keywords
Goblet Cell Associated Antigen Passages are Inhibited During Salmonella typhimurium Infection to Prevent Pathogen Dissemination and Limit Responses to Dietary Antigens
Sign Up to like & getrecommendations! Published in 2018 at "Mucosal immunology"
DOI: 10.1038/s41385-018-0007-6
Abstract: Dietary antigen acquisition by lamina propria (LP) dendritic cells (DCs) is crucial to induce oral tolerance and maintain homeostasis. However, encountering innocuous antigens during infection can lead to inflammatory responses, suggesting processes may limit steady-state… read more here.
Keywords: pathogen; cell associated; infection; antigen ... See more keywords
High expression of sonic hedgehog in allergic airway epithelia contributes to goblet cell metaplasia
Sign Up to like & getrecommendations! Published in 2018 at "Mucosal immunology"
DOI: 10.1038/s41385-018-0033-4
Abstract: Sonic hedgehog (SHH) is abundantly expressed and critical for morphogenesis in embryonic lungs; however, SHH expression drops to a much lower level in mice from E17.5 and in humans from the 21st gestational week. We… read more here.
Keywords: allergic airway; airway epithelia; sonic hedgehog; expression ... See more keywords