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   Articles with "goblet cells" as a keyword



Resolvin D2 uses multiple Ca2+‐dependent signaling pathways to stimulate mucin secretion in rat and human conjunctival goblet cells

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recommendations! Published in 2022 at "Journal of Cellular Physiology"

DOI: 10.1002/jcp.30854

Abstract: The mucin layer of the tear film is produced by goblet cells in the conjunctiva to protect the ocular surface and maintain homeostasis. The pro‐resolving lipid mediator resolvin D2 (RvD2) biosynthesized from an omega 3… read more here.

Keywords: ca2; rat; goblet cells; secretion ... See more keywords

Prenatal development and histochemical characteristics of gastrointestinal mucins in sheep fetuses

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recommendations! Published in 2018 at "Microscopy Research and Technique"

DOI: 10.1002/jemt.23018

Abstract: The object of this study was to describe the prenatal development and histochemical properties of mucins in the sheep gastrointestinal tract. To determine changes in the mucin profile, the sections were stained with specific histochemical… read more here.

Keywords: mucins sheep; acidic mucins; cells containing; development histochemical ... See more keywords
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2′-Fucosyllactose impacts the expression of mucus-related genes in goblet cells and maintains barrier function of gut epithelial cells

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recommendations! Published in 2021 at "Journal of Functional Foods"

DOI: 10.1016/j.jff.2021.104630

Abstract: Abstract Scope Cost-effective microbial biosynthesis of 2′-fucosyllactose (2′-FL) allows its application in infant formula. The specific effects of 2′-FL on the gastrointestinal immune barrier are still largely unknown. Methods/results Here, we quantified and compared the… read more here.

Keywords: mucus related; expression mucus; related genes; goblet cells ... See more keywords

Modifications of cholera toxin subunit B binding to human large intestinal epithelium. An immunohistochemical study.

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recommendations! Published in 2018 at "Microbial pathogenesis"

DOI: 10.1016/j.micpath.2018.08.047

Abstract: Binding of cholera toxin subunit B (CTB) to its receptor and toxin transport into the intestinal epithelial cells are the causative events for the potentially lethal disease cholera. The five sugar mono-sialo ganglioside GM1 is… read more here.

Keywords: ctb; toxin subunit; toxin; goblet cells ... See more keywords

Lactobacillus paracasei from koumiss ameliorates diarrhea in mice via tight junctions modulation.

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recommendations! Published in 2022 at "Nutrition"

DOI: 10.1016/j.nut.2021.111584

Abstract: OBJECTIVES Probiotics are gaining interest as alternative options for antibiotic or antiinflammatory drugs. Probiotics can affect the health of the host through metabolites and competitive inhibition adhesion of pathogenic microorganisms. Koumiss is an important part… read more here.

Keywords: expression; mice; goblet cells; koumiss ... See more keywords

Adolescent social isolation decreases colonic goblet cells and impairs spatial cognition through the reduction of cystine

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recommendations! Published in 2024 at "Molecular Psychiatry"

DOI: 10.1038/s41380-024-02826-9

Abstract: Negative experiences during adolescence, such as social isolation (SI), bullying, and abuse, increase the risk of psychiatric diseases in adulthood. However, the pathogenesis of psychiatric diseases induced by these factors remain poorly understood. In adolescents,… read more here.

Keywords: cystine; cognitive deficits; spatial cognitive; hip ... See more keywords
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ELEVATED ADENOMATOUS POLYPOSIS COLI IN GOBLET CELLS IS ASSOCIATED WITH INFLAMMATION IN MOUSE AND HUMAN COLON

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recommendations! Published in 2021 at "Gastroenterology"

DOI: 10.1053/j.gastro.2021.01.098

Abstract: New findings What is the central question of this study? What is the localization and distribution pattern of adenomatous polyposis coli (APC) in intestinal epithelial cells? Does this distribution change in different regions of the… read more here.

Keywords: expression; apc; goblet cells; adenomatous polyposis ... See more keywords

Stiffness Restricts the Stemness of the Intestinal Stem Cells and Skews Their Differentiation Towards Goblet Cells.

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recommendations! Published in 2023 at "Gastroenterology"

DOI: 10.1053/j.gastro.2023.02.030

Abstract: BACKGROUND & AIMS Fibrosis and tissue stiffening are hallmarks of the inflammatory bowel disease (IBD). We have hypothesized that the increased stiffness directly contributes to the dysregulation of the epithelial cell homeostasis in IBD. Here,… read more here.

Keywords: stiffness; goblet cells; yap; differentiation ... See more keywords

Goblet cells dictate viral tropism and pathogenesis in nasal and intestinal mucosae

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recommendations! Published in 2025 at "Proceedings of the National Academy of Sciences of the United States of America"

DOI: 10.1073/pnas.2514150122

Abstract: Significance We identify goblet cells as regulators of viral infections at mucosal surfaces. Goblet cell-derived mucus effectively shields nasal and intestinal epithelia from swine influenza virus (SIV) and porcine epidemic diarrhea virus (PEDV), with virus-driven… read more here.

Keywords: dictate viral; goblet; cells dictate; pathogenesis ... See more keywords
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An intercrypt subpopulation of goblet cells is essential for colonic mucus barrier function

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recommendations! Published in 2021 at "Science"

DOI: 10.1126/science.abb1590

Abstract: Goblet cell diversity An adult human has a gut surface area averaging 30 square meters that is bombarded daily by xenobiotics and microorganisms. Mucus synthesized by goblet cells supplies a protective barrier coating. Nyström et… read more here.

Keywords: mucus barrier; surface; mucus; colitis ... See more keywords

Clearance of small intestinal crypts involves goblet cell mucus secretion by intracellular granule rupture and enterocyte ion transport

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recommendations! Published in 2022 at "Science Signaling"

DOI: 10.1126/scisignal.abl5848

Abstract: Goblet cells in the small intestinal crypts contain large numbers of mucin granules that are rapidly discharged to clean bacteria from the crypt. Because acetylcholine released by neuronal and nonneuronal cells controls many aspects of… read more here.

Keywords: mucus secretion; goblet; crypt; goblet cells ... See more keywords