Resolvin D2 uses multiple Ca2+‐dependent signaling pathways to stimulate mucin secretion in rat and human conjunctival goblet cells
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.30854
Abstract: The mucin layer of the tear film is produced by goblet cells in the conjunctiva to protect the ocular surface and maintain homeostasis. The pro‐resolving lipid mediator resolvin D2 (RvD2) biosynthesized from an omega 3… read more here.
Keywords: ca2; rat; goblet cells; secretion ... See more keywords
Prenatal development and histochemical characteristics of gastrointestinal mucins in sheep fetuses
Sign Up to like & getrecommendations! Published in 2018 at "Microscopy Research and Technique"
DOI: 10.1002/jemt.23018
Abstract: The object of this study was to describe the prenatal development and histochemical properties of mucins in the sheep gastrointestinal tract. To determine changes in the mucin profile, the sections were stained with specific histochemical… read more here.
Keywords: mucins sheep; acidic mucins; cells containing; development histochemical ... See more keywords
2′-Fucosyllactose impacts the expression of mucus-related genes in goblet cells and maintains barrier function of gut epithelial cells
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Functional Foods"
DOI: 10.1016/j.jff.2021.104630
Abstract: Abstract Scope Cost-effective microbial biosynthesis of 2′-fucosyllactose (2′-FL) allows its application in infant formula. The specific effects of 2′-FL on the gastrointestinal immune barrier are still largely unknown. Methods/results Here, we quantified and compared the… read more here.
Keywords: mucus related; expression mucus; related genes; goblet cells ... See more keywords
Modifications of cholera toxin subunit B binding to human large intestinal epithelium. An immunohistochemical study.
Sign Up to like & getrecommendations! Published in 2018 at "Microbial pathogenesis"
DOI: 10.1016/j.micpath.2018.08.047
Abstract: Binding of cholera toxin subunit B (CTB) to its receptor and toxin transport into the intestinal epithelial cells are the causative events for the potentially lethal disease cholera. The five sugar mono-sialo ganglioside GM1 is… read more here.
Keywords: ctb; toxin subunit; toxin; goblet cells ... See more keywords
Lactobacillus paracasei from koumiss ameliorates diarrhea in mice via tight junctions modulation.
Sign Up to like & getrecommendations! Published in 2022 at "Nutrition"
DOI: 10.1016/j.nut.2021.111584
Abstract: OBJECTIVES Probiotics are gaining interest as alternative options for antibiotic or antiinflammatory drugs. Probiotics can affect the health of the host through metabolites and competitive inhibition adhesion of pathogenic microorganisms. Koumiss is an important part… read more here.
Keywords: expression; mice; goblet cells; koumiss ... See more keywords
ELEVATED ADENOMATOUS POLYPOSIS COLI IN GOBLET CELLS IS ASSOCIATED WITH INFLAMMATION IN MOUSE AND HUMAN COLON
Sign Up to like & getrecommendations! Published in 2021 at "Gastroenterology"
DOI: 10.1053/j.gastro.2021.01.098
Abstract: New findings What is the central question of this study? What is the localization and distribution pattern of adenomatous polyposis coli (APC) in intestinal epithelial cells? Does this distribution change in different regions of the… read more here.
Keywords: expression; apc; goblet cells; adenomatous polyposis ... See more keywords
Stiffness Restricts the Stemness of the Intestinal Stem Cells and Skews Their Differentiation Towards Goblet Cells.
Sign Up to like & getrecommendations! Published in 2023 at "Gastroenterology"
DOI: 10.1053/j.gastro.2023.02.030
Abstract: BACKGROUND & AIMS Fibrosis and tissue stiffening are hallmarks of the inflammatory bowel disease (IBD). We have hypothesized that the increased stiffness directly contributes to the dysregulation of the epithelial cell homeostasis in IBD. Here,… read more here.
Keywords: stiffness; goblet cells; yap; differentiation ... See more keywords
An intercrypt subpopulation of goblet cells is essential for colonic mucus barrier function
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DOI: 10.1126/science.abb1590
Abstract: Goblet cell diversity An adult human has a gut surface area averaging 30 square meters that is bombarded daily by xenobiotics and microorganisms. Mucus synthesized by goblet cells supplies a protective barrier coating. Nyström et… read more here.
Keywords: mucus barrier; surface; mucus; colitis ... See more keywords
Clearance of small intestinal crypts involves goblet cell mucus secretion by intracellular granule rupture and enterocyte ion transport
Sign Up to like & getrecommendations! Published in 2022 at "Science Signaling"
DOI: 10.1126/scisignal.abl5848
Abstract: Goblet cells in the small intestinal crypts contain large numbers of mucin granules that are rapidly discharged to clean bacteria from the crypt. Because acetylcholine released by neuronal and nonneuronal cells controls many aspects of… read more here.
Keywords: mucus secretion; goblet; crypt; goblet cells ... See more keywords
Effects of Yacon on Colonic IFN-γ and Goblet Cells of the 2,4,6-Trinitrobenzene Sulfonic Acid-Induced Colitis Mouse Model
Sign Up to like & getrecommendations! Published in 2020 at "Iranian Biomedical Journal"
DOI: 10.29252/ibj.24.5.276
Abstract: Background: IBD is a chronic inflammatory condition associated with damage to the intestinal mucosal barrier. Supplementation of yacon tubers has been known to have positive effect on intestinal health. Therefore, we conducted the present study… read more here.
Keywords: ifn; colitis mouse; colitis; goblet cells ... See more keywords
Conjunctival Goblet Cell Responses to TLR5 Engagement Promote Activation of Local Antigen-Presenting Cells
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.716939
Abstract: Conjunctival epithelium forms a barrier between the ocular surface microbial flora and the ocular mucosa. In addition to secreting gel-forming mucins, goblet cells, located in the conjunctival epithelium, help maintain local immune homeostasis by secreting… read more here.
Keywords: ocular mucosal; goblet; dendritic cells; goblet cells ... See more keywords