Synthesis, X-ray structure, DFT calculations and anticancer activity of a selenourea coordinated gold(I)-carbene complex
Sign Up to like & getrecommendations! Published in 2017 at "Polyhedron"
DOI: 10.1016/j.poly.2017.08.003
Abstract: Abstract A gold(I)-carbene complex, [Au(IPr)(Seu)]PF6 (1), where Seu = Selenourea and IPr = 1,3-Bis(2,6-diisopropylphenyl)imidazol-2-ylidene, was prepared using [Au(IPr)Cl] and characterized by elemental analysis, IR, and NMR (1H, 13C, 77Se) methods. The crystal structure of 1 was determined by single-crystal… read more here.
Keywords: seu; carbene complex; gold carbene; ipr ... See more keywords
Interrupting the [Au]-Catalyzed Nitroalkyne Cycloisomerization: Trapping the Putative α-Oxo Gold Carbene with Benzo[c]isoxazole.
Sign Up to like & getrecommendations! Published in 2021 at "Organic letters"
DOI: 10.1021/acs.orglett.1c00539
Abstract: The [Au]-catalyzed nitroalkyne cycloisomerization of 2-alkynylnitrobenzenes leading to anthranils has been interrupted by possible trapping of the postulated intermediate α-oxo gold carbene with an external nucleophile such as benzo[c]isoxazole (anthranil). At the outset, this provides… read more here.
Keywords: nitroalkyne cycloisomerization; oxo gold; benzo isoxazole; gold carbene ... See more keywords
Synthesis of α-Ketoamides via Gold(I) Carbene Intermediates.
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DOI: 10.1021/acs.orglett.2c01489
Abstract: α-Ketoamides have been found to be an important functional group in a broad spectrum of inhibitors such as the Corona virus and other viruses. Here we report an unprecedented gold-catalyzed 2-fold reaction of a bromoalkyne… read more here.
Keywords: carbene intermediates; synthesis ketoamides; ketoamides via; gold carbene ... See more keywords