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   Articles with "gold complex" as a keyword



Self-Assembled Iron(III) Coordination Cage as an MRI-Active Carrier for a Gold(I) Drug.

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recommendations! Published in 2024 at "Bioconjugate chemistry"

DOI: 10.1021/acs.bioconjchem.4c00391

Abstract: A T1 MRI probe based on a self-assembled coordination cage with four iron(III) centers acts as a host for the hydrolysis product of the gold(I) anticancer drug, Au(PEt3)Cl. 1H NMR characterization of the gold complex… read more here.

Keywords: iii; gold complex; cage; coordination cage ... See more keywords

Erlotinib-Gold(I) Complex Induces Leukemia Cell DC Differentiation and Remodels the Immunosuppressive Microenvironment.

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recommendations! Published in 2024 at "Journal of medicinal chemistry"

DOI: 10.1021/acs.jmedchem.4c01354

Abstract: Inducing differentiation of leukemia cells into dendritic cells (DC) is pivotal to reshaping the immunosuppressive microenvironment. Here, we report the synthesis of EG2, an erlotinib-gold(I) complex, which directly prompts the differentiation of acute myeloid leukemia… read more here.

Keywords: differentiation; immunosuppressive microenvironment; gold complex; erlotinib gold ... See more keywords
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Lenalidomide (LENA) Hybrid Gold Complex Nanoparticles: Synthesis, Physicochemical Evaluation, and Perspectives in Nanomedicine

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recommendations! Published in 2020 at "ACS Omega"

DOI: 10.1021/acsomega.0c02644

Abstract: This paper proposes a fast methodology to synthesize hybrid lenalidomide gold nanoparticles. Gold (HAuCl4) is chelated with an antiangiogenic compound (lenalidomide (LENA)) and diacid poly(ethylene glycol) (PEG) as capping agent and reagent. The suggested synthesis… read more here.

Keywords: hybrid gold; lenalidomide lena; drug; gold ... See more keywords

A novel cyclic dinuclear gold(I) complex induces anticancer activity via an oxidative stress-mediated intrinsic apoptotic pathway in MDA-MB-231 cancer cells.

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recommendations! Published in 2022 at "Dalton transactions"

DOI: 10.1039/d1dt03546k

Abstract: A new dinuclear cyclic gold(I) complex [Au2(DCyPA)2](PF6)2, 1, based on bis[2-(dicyclohexylphosphano)ethyl]amine (DCyPA) has been synthesized and characterized by elemental analysis, IR and NMR spectroscopy, and X-ray crystallography. In the dinuclear complex cation [Au2(DCyPA)2]2+, the two… read more here.

Keywords: via oxidative; gold complex; cancer cells; mda 231 ... See more keywords