Articles with "gold mediated" as a keyword



Photo by teveir from unsplash

Gold(I)-Mediated Rapid Cyclization of Propargylated Peptides via Imine Formation

Sign Up to like & get
recommendations!
Published in 2022 at "Journal of the American Chemical Society"

DOI: 10.1021/jacs.1c12906

Abstract: In fundamental research and drug discovery, there is still a need for effective and straightforward chemical approaches for generating cyclic peptides. The divergent synthesis of cyclic peptides remains a challenge, in particular when cyclization is… read more here.

Keywords: cyclic peptides; gold mediated; rapid cyclization; imine ... See more keywords
Photo by infinitygraphy from unsplash

Gold mediated sp3αC-H functionalization of steroidal diglycoside and their anti-cancer evaluation

Sign Up to like & get
recommendations!
Published in 2019 at "Natural Product Research"

DOI: 10.1080/14786419.2019.1696789

Abstract: Abstract C(sp3)-H alkylation at α-position of methyl-keto group on D-ring of Steroidal diglycoside (SG) with (i) C=N of Schiff base imines to form amine derivatives and (ii) C=C of acrylate Michael acceptors to form Markovnikov… read more here.

Keywords: steroidal diglycoside; sp3 functionalization; mediated sp3; cancer ... See more keywords