Anti-Amyloidogenic and Fibril-Disaggregating Potency of the Levodopa-Functionalized Gold Nanoroses as Exemplified in a Diphenylalanine-Based Amyloid Model.
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DOI: 10.1021/acs.bioconjchem.2c00007
Abstract: The phenomenon of proteins/peptide assembly into amyloid fibrils is associated with various neurodegenerative and age-related human disorders. Inhibition of the aggregation behavior of amyloidogenic peptides/proteins or disruption of the pre-formed aggregates is a viable therapeutic… read more here.
Keywords: gold nanoroses; potency; functionalized gold; levodopa functionalized ... See more keywords