The golden (Syrian) hamster as a model for the study of reproductive biology: Past, present, and future
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DOI: 10.1002/rmb2.12241
Abstract: The golden (Syrian) hamster (Mesocricetus auratus) is a small rodent that belongs to the Cricetidae family. It has several unique features that are advantageous for the study of reproductive and developmental biology, including a consistent… read more here.
Keywords: hamster model; golden syrian; study reproductive; syrian hamster ... See more keywords
Pathobiology and dysbiosis of the respiratory and intestinal microbiota in 14 months old Golden Syrian hamsters infected with SARS-CoV-2
Sign Up to like & getrecommendations! Published in 2022 at "PLOS Pathogens"
DOI: 10.1371/journal.ppat.1010734
Abstract: The pandemic of severe acute respiratory syndrome coronavirus 2 (SARS2) affected the geriatric population. Among research models, Golden Syrian hamsters (GSH) are one of the most representative to study SARS2 pathogenesis and host responses. However,… read more here.
Keywords: sars2 infection; infection; sars cov; golden syrian ... See more keywords
Comparison of protective effects of hesperetin and pectolinarigenin on high-fat diet-induced hyperlipidemia and hepatic steatosis in Golden Syrian hamsters
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DOI: 10.1538/expanim.22-0115
Abstract: A comparative study was conducted to determine whether hesperetin and pectolinarigenin could lower total cholesterol (TC), triglycerides (TG), low-density lipoprotein cholesterol (LDL), and high-density lipoprotein cholesterol (HDL) in a high-fat diet (HFD)-induced high lipid model… read more here.
Keywords: golden syrian; high fat; hepatic steatosis; hesperetin pectolinarigenin ... See more keywords
Intranasal delivery of a chimpanzee adenovirus vector expressing a pre-fusion spike (BV-AdCoV-1) protects golden Syrian hamsters against SARS-CoV-2 infection
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2022.979641
Abstract: We evaluated the immunogenicity and protective ability of a chimpanzee replication-deficient adenovirus vectored COVID-19 vaccine (BV-AdCoV-1) expressing a stabilized pre-fusion SARS-CoV-2 spike glycoprotein in golden Syrian hamsters. Intranasal administration of BV-AdCoV-1 elicited strong humoral and… read more here.
Keywords: pre fusion; syrian hamsters; infection; adcov ... See more keywords
YangXue QingNao Wan and Silibinin Capsules, the Two Chinese Medicines, Attenuate Cognitive Impairment in Aged LDLR (+/-) Golden Syrian Hamsters Involving Protection of Blood Brain Barrier
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DOI: 10.3389/fphys.2018.00658
Abstract: The purpose of the study was to explore the effect and the underlying mechanism of YangXue QingNao Wan (YXQNW) and Silibinin Capsules (SC), the two Chinese medicines, on cognitive impairment in older people with familial… read more here.
Keywords: golden syrian; microscopy; syrian hamsters; ldlr golden ... See more keywords
Infection with Seasonal H1N1 Influenza Results in Comparable Disease Kinetics and Host Immune Responses in Ferrets and Golden Syrian Hamsters
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DOI: 10.3390/pathogens12050668
Abstract: Animal models of influenza are important in preclinical research for the study of influenza infection and the assessment of vaccines, drugs and therapeutics. Here, we show that Golden Syrian hamsters (Mesocricetus auratus) inoculated via the… read more here.
Keywords: comparable disease; infection seasonal; immune responses; golden syrian ... See more keywords
SARS-CoV-2 Disease Severity in the Golden Syrian Hamster Model of Infection Is Related to the Volume of Intranasal Inoculum
Sign Up to like & getrecommendations! Published in 2023 at "Viruses"
DOI: 10.3390/v15030748
Abstract: The golden Syrian hamster (Mesocricetus auratus) is now commonly used in preclinical research for the study of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and the assessment of vaccines, drugs and therapeutics. Here, we… read more here.
Keywords: volume; golden syrian; severity; syrian hamster ... See more keywords
Efficacy of Plant-Made Human Recombinant ACE2 against COVID-19 in a Golden Syrian Hamster Model
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DOI: 10.3390/v15040964
Abstract: Coronavirus disease 2019 (COVID-19) is a novel infectious respiratory disease caused by SARS-CoV-2. We evaluated the efficacy of a plant-based human recombinant angiotensin-converting enzyme 2 (hrACE2) and hrACE2-foldon (hrACE2-Fd) protein against COVID-19. In addition, we… read more here.
Keywords: efficacy plant; golden syrian; hrace2 hrace2; hrace2 ... See more keywords
The Omicron Sub-Variant BA.4 Displays a Remarkable Lack of Clinical Signs in a Golden Syrian Hamster Model of SARS-CoV-2 Infection
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DOI: 10.3390/v15051133
Abstract: The ongoing emergence of SARS-CoV-2 virus variants remains a source of concern because it is accompanied by the potential for increased virulence as well as evasion of immunity. Here we show that, although having an… read more here.
Keywords: infection; hamster model; golden syrian; syrian hamster ... See more keywords