Clustering in the Golgi apparatus governs sorting and function of GPI‐APs in polarized epithelial cells
Sign Up to like & getrecommendations! Published in 2019 at "FEBS Letters"
DOI: 10.1002/1873-3468.13573
Abstract: Glycosylphosphatidylinositol‐anchored proteins (GPI‐APs) are lipid APs attached to the extracellular leaflet of the plasma membrane (PM) via a glycolipid anchor. GPI‐APs are commonly associated with cholesterol‐ and sphingolipid‐enriched membrane microdomains. These microdomains help regulating various… read more here.
Keywords: golgi apparatus; gpi aps; gpi; polarized epithelial ... See more keywords
Disulfide bond formation and redox regulation in the Golgi apparatus
Sign Up to like & getrecommendations! Published in 2022 at "FEBS Letters"
DOI: 10.1002/1873-3468.14510
Abstract: Formation of disulfide bonds in secreted and cell‐surface proteins involves numerous enzymes and chaperones abundant in the endoplasmic reticulum (ER), the first and main site for disulfide bonding in the secretory pathway. Although the Golgi… read more here.
Keywords: disulfide; formation; golgi apparatus; golgi ... See more keywords
The role of metal ions in the Golgi apparatus
Sign Up to like & getrecommendations! Published in 2022 at "Cell Biology International"
DOI: 10.1002/cbin.11848
Abstract: The Golgi apparatus is a membrane‐bound organelle that functions as a central role in the secretory pathway. Since the discovery of the Golgi apparatus, its structure and function have attracted ever‐increasing attention from researchers. Recently,… read more here.
Keywords: metal ions; role metal; golgi apparatus;
Changes in human Golgi apparatus reflect new left ventricular dimensions and function in dilated cardiomyopathy patients
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Heart Failure"
DOI: 10.1002/ejhf.671
Abstract: Dilated cardiomyopathy (DCM) is a progressive disease characterized by ventricular chamber enlargement and contractile dysfunction. Natriuretic peptides (NPs) are state of the art for diagnosis and prognosis.1 Their secretion appears to depend on cardiac location,2… read more here.
Keywords: dimensions function; human golgi; golgi; golgi apparatus ... See more keywords
Cascade Delivery to Golgi Apparatus and On-Site Formation of Subcellular Drug Reservoir for Cancer Metastasis Suppression.
Sign Up to like & getrecommendations! Published in 2022 at "Small"
DOI: 10.1002/smll.202204747
Abstract: As the foremost cause of cancer-related death, metastasis consists of three steps: invasion, circulation, and colonization. Only targeting one single phase of the metastasis cascade may be insufficient since there are many alternative routes for… read more here.
Keywords: metastasis; cascade; cancer; golgi apparatus ... See more keywords
The Golgi apparatus is the main microtubule-organizing center in differentiating skeletal muscle cells.
Sign Up to like & getrecommendations! Published in 2021 at "Histochemistry and cell biology"
DOI: 10.1007/s00418-021-01999-6
Abstract: Studies in differentiating skeletal muscle cells in vitro have revealed that the microtubule-organizing center shifts from the centrosome to the perinuclear sites. As the Golgi apparatus surrounds the nucleus in a myotube, it is unclear… read more here.
Keywords: skeletal muscle; microtubule; differentiating skeletal; muscle cells ... See more keywords
Three-dimensional reconstruction of the Golgi apparatus in osteoclasts by a combination of NADPase cytochemistry and serial section scanning electron microscopy.
Sign Up to like & getrecommendations! Published in 2021 at "Histochemistry and cell biology"
DOI: 10.1007/s00418-021-02024-6
Abstract: The three-dimensional morphology of the Golgi apparatus in osteoclasts was investigated by computer-aided reconstruction. Rat femora were treated for nicotinamide adenine dinucleotide phosphatase (NADPase) cytochemistry, and light microscopy was used to select several osteoclasts in… read more here.
Keywords: three dimensional; golgi apparatus; nadpase cytochemistry; microscopy ... See more keywords
Searching for combination therapy by clustering methods: Stimulation of PKC in Golgi apparatus combined with hypericin induced PDT.
Sign Up to like & getrecommendations! Published in 2020 at "Photodiagnosis and photodynamic therapy"
DOI: 10.1016/j.pdpdt.2020.101813
Abstract: Cancer cells metabolism is nowadays a very attractive target of anticancer treatments. This work focuses on protein kinase C (PKC) signaling in the U87 MG glioma. By means of western blot, fluorescence and time-resolved fluorescence… read more here.
Keywords: combination therapy; hypericin; golgi apparatus; therapy ... See more keywords
In situ Fluorescent and Photoacoustic Imaging of Golgi pH to Elucidate the Function of Transmembrane Protein 165.
Sign Up to like & getrecommendations! Published in 2020 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.9b04709
Abstract: Golgi pH homeostasis affects many different biological processes, including glycosylation. Recent studies have demonstrated that transmembrane protein 165 (TMEM165) deficiency leads to Golgi glycosylation abnormalities by disturbing Golgi pH homeostasis. However, due to the lack… read more here.
Keywords: golgi; golgi homeostasis; protein 165; golgi apparatus ... See more keywords
A Self-Assembling Probe for Imaging the States of Golgi Apparatus in Live Single Cells.
Sign Up to like & getrecommendations! Published in 2022 at "Bioconjugate chemistry"
DOI: 10.1021/acs.bioconjchem.2c00084
Abstract: Despite the enormous progress in genomics and proteomics, it is still challenging to assess the states of organelles in living cells with high spatiotemporal resolution. Based on our recent finding of enzyme-instructed self-assembly of a… read more here.
Keywords: imaging states; golgi apparatus; self assembling; assembling probe ... See more keywords
Manganese Mapping Using a Fluorescent Mn2+ Sensor and Nanosynchrotron X-ray Fluorescence Reveals the Role of the Golgi Apparatus as a Manganese Storage Site.
Sign Up to like & getrecommendations! Published in 2019 at "Inorganic chemistry"
DOI: 10.1021/acs.inorgchem.9b01389
Abstract: Elucidating dynamics in transition-metal distribution and localization under physiological and pathophysiological conditions is central to our understanding of metal-ion regulation. In this Forum Article, we focus on manganese and specifically recent developments that point to… read more here.
Keywords: storage; golgi apparatus; apparatus manganese; role golgi ... See more keywords