The Golgi complex: 120 years and it doesn't show
Sign Up to like & getrecommendations! Published in 2019 at "FEBS Letters"
DOI: 10.1002/1873-3468.13577
Abstract: Hundred and twenty years after its discovery, the Golgi complex still attracts the interest of cell biologists, and many yet open questions address both ‘old’ and ‘new’ aspects of its function. Over this long period,… read more here.
Keywords: golgi complex; era; golgi; special issue ... See more keywords
The alpha-1,2 fucosylated tubule system of DU145 prostate cancer cells is derived from a partially fragmented Golgi complex and its formation is actin-dependent.
Sign Up to like & getrecommendations! Published in 2020 at "Experimental cell research"
DOI: 10.1016/j.yexcr.2020.112324
Abstract: In previous work, we showed that highly proliferative cells and cancer cells, but not cells with normal growth rate, have tubules rich in alpha-1,2 fucosylated epitopes that extend radially from the nucleus to the cell… read more here.
Keywords: golgi complex; golgi; prostate cancer; alpha fucosylated ... See more keywords
Distinct regulations of ARF1 by two Aplysia Sec7 isoforms
Sign Up to like & getrecommendations! Published in 2017 at "Animal Cells and Systems"
DOI: 10.1080/19768354.2016.1276025
Abstract: ABSTRACT Sec7 protein is a guanine nucleotide exchange factor in the ADP-ribosylation factor (ARF) family of small GTP-binding proteins. Aplysia Sec7 proteins (ApSec7s) play many roles in neurite outgrowth and synaptic facilitation in Aplysia neurons.… read more here.
Keywords: apsec7; golgi complex; sec7; aplysia sec7 ... See more keywords
Chlamydia Hijacks ARF GTPases To Coordinate Microtubule Posttranslational Modifications and Golgi Complex Positioning
Sign Up to like & getrecommendations! Published in 2017 at "mBio"
DOI: 10.1128/mbio.02280-16
Abstract: ABSTRACT The intracellular bacterium Chlamydia trachomatis develops in a parasitic compartment called the inclusion. Posttranslationally modified microtubules encase the inclusion, controlling the positioning of Golgi complex fragments around the inclusion. The molecular mechanisms by which… read more here.
Keywords: inclusion; golgi complex; around inclusion; chlamydia ... See more keywords
Identification and characterisation of a cryptic Golgi complex in Naegleria gruberi
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cell Science"
DOI: 10.1242/jcs.213306
Abstract: ABSTRACT Although the Golgi complex has a conserved morphology of flattened stacked cisternae in most eukaryotes, it has lost the stacked organisation in several lineages, raising the question of what range of morphologies is possible… read more here.
Keywords: golgi complex; golgi; complex naegleria; cryptic golgi ... See more keywords
Supply chain logistics – the role of the Golgi complex in extracellular matrix production and maintenance
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cell Science"
DOI: 10.1242/jcs.258879
Abstract: ABSTRACT The biomechanical and biochemical properties of connective tissues are determined by the composition and quality of their extracellular matrix. This, in turn, is highly dependent on the function and organisation of the secretory pathway.… read more here.
Keywords: matrix; extracellular matrix; golgi complex; golgi ... See more keywords
The GalNAc-T Activation Pathway (GALA) is not a general mechanism for regulating mucin-type O-glycosylation
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0179241
Abstract: Mucin-type O-glycosylation is initiated by the UDP-GalNAc polypeptide:N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. Their activity results in the GalNAc α1-O-Thr/Ser structure, termed the Tn antigen, which is further decorated with additional sugars. In neoplastic cells, the… read more here.
Keywords: golgi complex; mechanism; mucin type; type glycosylation ... See more keywords
The Golgi complex: a hub of the secretory pathway
Sign Up to like & getrecommendations! Published in 2021 at "BMB Reports"
DOI: 10.5483/bmbrep.2021.54.5.270
Abstract: The Golgi complex plays a central role in protein secretion by regulating cargo sorting and trafficking. As these processes are of functional importance to cell polarity, motility, growth, and division, there is considerable interest in… read more here.
Keywords: golgi; biology; golgi complex; complex hub ... See more keywords