Protective effects of recombinant human golimumab and pentoxifylline in nephrotoxicity induced by cisplatin
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.22990
Abstract: In cisplatin‐induced nephrotoxicity, the significant role of activation of inflammatory pathways has been reported earlier. Studies indicate elevated expression and activity of tumor necrosis factor‐α (TNF‐α) in both, serum and kidneys of cisplatin‐treated animals. Golimumab,… read more here.
Keywords: inflammation; golimumab; oxidative stress; cisplatin ... See more keywords
Golimumab effectiveness in biologic inadequate responding patients with rheumatoid arthritis, psoriatic arthritis and spondyloarthritis in real-life from the Italian registry GISEA.
Sign Up to like & getrecommendations! Published in 2020 at "Joint bone spine"
DOI: 10.1016/j.jbspin.2020.07.011
Abstract: OBJECTIVE To evaluate the clinical effectiveness of golimumab in biologic inadequate responder (IR) patients with Rheumatoid arthritis (RA), Spondyloarthritis (SpA), and Psoriatic arthritis (PsA). METHODS We analyzed 1424 patients on golimumab from the GISEA registry.… read more here.
Keywords: golimumab; biologic biologics; effectiveness; biologic inadequate ... See more keywords
PMS97 - A Multi-Centre Retrospective Study To Describe The Impact on Healthcare Resource Use And Real World Effectiveness of Golimumab In Ankylosing Spondylitis (AS) In UK Clinical Practice
Sign Up to like & getrecommendations! Published in 2017 at "Value in Health"
DOI: 10.1016/j.jval.2017.08.820
Abstract: Objectives Study aims were to describe the impact of Tumour Necrosis Factor-α (TNF-α) inhibitor golimumab on UK real-world healthcare resource use (HRU) and evaluate the clinical effectiveness of golimumab in the treatment of Ankylosing Spondylitis… read more here.
Keywords: real world; describe impact; ankylosing spondylitis; golimumab ... See more keywords
Golimumab in real-life settings: 2 Years drug survival and predictors of clinical outcomes in rheumatoid arthritis, spondyloarthritis, and psoriatic arthritis.
Sign Up to like & getrecommendations! Published in 2017 at "Seminars in arthritis and rheumatism"
DOI: 10.1016/j.semarthrit.2017.01.008
Abstract: OBJECTIVES To assess the drug survival of golimumab, and predictors thereof, in patients affected with rheumatoid arthritis (RA), spondyloarthritis (SpA), and psoriatic arthritis (PsA) in a prospective observational cohort. METHODS This is a non-interventional, longitudinal… read more here.
Keywords: drug survival; golimumab; drug; discontinuation ... See more keywords
Rapid and Sustained Efficacy of Golimumab in the Treatment of Multirefractory Uveitis Associated with Behçet’s Disease
Sign Up to like & getrecommendations! Published in 2019 at "Ocular Immunology and Inflammation"
DOI: 10.1080/09273948.2017.1351573
Abstract: ABSTRACT Purpose: To evaluate golimumab (GOL) efficacy in the management of Behçet’s disease (BD)-related uveitis. Methods: We retrospectively collected data from 5 patients (8 eyes) with at least two recent relapses of uveitis, treated with… read more here.
Keywords: rapid sustained; sustained efficacy; golimumab; beh disease ... See more keywords
Efficacy of golimumab for preventing large joint destruction in patients with rheumatoid arthritis as determined by the ARASHI score
Sign Up to like & getrecommendations! Published in 2017 at "Modern Rheumatology"
DOI: 10.1080/14397595.2017.1280113
Abstract: Abstract Objectives: The objective of this study is to investigate the inhibitory effect of golimumab on large joint destruction in patients with rheumatoid arthritis. Methods: We recruited 45 patients with rheumatoid arthritis and evaluated the… read more here.
Keywords: large joint; golimumab; rheumatoid arthritis; score ... See more keywords
Golimumab in the treatment of psoriatic arthritis
Sign Up to like & getrecommendations! Published in 2018 at "Expert Review of Clinical Immunology"
DOI: 10.1080/1744666x.2018.1524755
Abstract: ABSTRACT Introduction: Psoriatic arthritis (PsA) is an inflammatory arthritis that can be aggressive and destructive, resulting in significant morbidity. While many new agents have been approved for the treatment of PsA over the past decade,… read more here.
Keywords: psoriatic arthritis; psa; golimumab treatment; treatment ... See more keywords
Two years follow-up of golimumab treatment in refractory enteropathic spondyloarthritis patients with Crohn disease: A STROBE-compliant study.
Sign Up to like & getrecommendations! Published in 2021 at "Medicine"
DOI: 10.1097/md.0000000000025122
Abstract: ABSTRACT Golimumab is a fully human monoclonal antibody against tumor necrosis factor (TNF) approved for the treatment of ulcerative colitis and not for Crohn disease (CD). Many CD patients experience primary, secondary failure, or intolerance… read more here.
Keywords: golimumab treatment; treatment; spondyloarthritis; golimumab ... See more keywords
Subcutaneous golimumab for children with active polyarticular-course juvenile idiopathic arthritis: results of a multicentre, double-blind, randomised-withdrawal trial
Sign Up to like & getrecommendations! Published in 2018 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2016-210456
Abstract: Objective This report aims to determine the safety, pharmacokinetics (PK) and efficacy of subcutaneous golimumab in active polyarticular-course juvenile idiopathic arthritis (polyJIA). Methods In this three-part randomised double-blinded placebo-controlled withdrawal trial, all patients received open-label… read more here.
Keywords: active polyarticular; trial; part; jia ... See more keywords
Early MOnitoring of REsponse (MORE) to Golimumab Therapy: Results of a Multicentre, Prospective Observational Trial
Sign Up to like & getrecommendations! Published in 2022 at "Digestive Diseases"
DOI: 10.1159/000527460
Abstract: Background: The therapeutic goal of clinical remission in patients with moderate to severe ulcerative colitis (UC) is achieved after biological therapy only in 16–39%. Individualization of therapeutic intervention would benefit from prediction of early response.… read more here.
Keywords: clinical response; therapy; response week; week ... See more keywords