Articles with "golph3" as a keyword



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Circular GOLPH3 RNA exerts oncogenic effects in vitro by regulating the miRNA-1299/LIF axis in oral squamous cell carcinoma

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Published in 2022 at "Bioengineered"

DOI: 10.1080/21655979.2022.2067288

Abstract: ABSTRACT Circular RNAs, which are a novel subclass of noncoding RNAs, are reported to be involved in various biological processes. Aberrant expression of circular RNAs may promote cancer progression. The function of circular GOLPH3 RNA… read more here.

Keywords: cell; 1299 lif; lif axis; golph3 ... See more keywords
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Long Intergenic Noncoding RNA 00641 Promotes Growth and Invasion of Colorectal Cancer through Regulating miR-450b-5p/GOLPH3 Axis

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Published in 2022 at "Journal of Oncology"

DOI: 10.1155/2022/8259135

Abstract: Background Long noncoding RNAs (lncRNAs) have a vital function in tumor onset and progress. For instance, long intergenic noncoding RNA 00641 (LINC00641) has been linked to cancer modulation. Nonetheless, the precise biological roles of LINC00641… read more here.

Keywords: linc00641; golph3; long intergenic; mir 450b ... See more keywords
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Golgi Phosphoprotein 3 Promotes Wls Recycling and Wnt Secretion in Glioma Progression

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Published in 2018 at "Cellular Physiology and Biochemistry"

DOI: 10.1159/000491618

Abstract: Background/Aims: Golgi phosphoprotein 3 (GOLPH3) plays pro-malignancy roles in several types of cancer. However, the molecular mechanism underlying GOLPH3 promoting tumor progression remains poorly understood. Methods: The expression of GOLPH3 and Wntless (Wls) in glioma… read more here.

Keywords: wls recycling; secretion; glioma; golgi phosphoprotein ... See more keywords
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ATF-3/miR-590/GOLPH3 signaling pathway regulates proliferation of breast cancer

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Published in 2018 at "BMC Cancer"

DOI: 10.1186/s12885-018-4031-4

Abstract: BackgroundBreast cancer is one of the leading causes of death in women worldwide. Fast growth is the important character of breast cancer, which makes sure the subsequent metastasize and invasion breast cancer. Golgi related genes… read more here.

Keywords: breast; mir 590; proliferation; breast cancer ... See more keywords
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The knocking down of the oncoprotein Golgi phosphoprotein 3 in T98G cells of glioblastoma multiforme disrupts cell migration by affecting focal adhesion dynamics in a focal adhesion kinase-dependent manner

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Published in 2019 at "PLoS ONE"

DOI: 10.1371/journal.pone.0212321

Abstract: Golgi phosphoprotein 3 (GOLPH3) is a conserved protein of the Golgi apparatus that in humans has been implicated in tumorigenesis. However, the precise function of GOLPH3 in malignant transformation is still unknown. Nevertheless, clinicopathological data… read more here.

Keywords: t98g cells; cell migration; focal adhesion; golph3 ... See more keywords
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Golgi phosphoprotein-3 (GOLPH3) promote metastasis of nasopharyngeal carcinoma through regulating E-cadherin.

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Published in 2020 at "European review for medical and pharmacological sciences"

DOI: 10.26355/eurrev_202009_22827

Abstract: OBJECTIVE The purpose of this study was to investigate GOLPH3 expression in nasopharyngeal carcinoma (NPC) and its influence on the metastatic ability of NPC cells; meanwhile, the underlying mechanism of GOLPH3 promoting the malignant progression… read more here.

Keywords: npc; golph3 expression; metastasis; cell ... See more keywords
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Role of GOLPH3 and TPX2 in Neuroblastoma DNA Damage Response and Cell Resistance to Chemotherapy

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Published in 2019 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms20194764

Abstract: Neuroblastoma (NB) is an aggressive, relapse-prone infancy tumor of the sympathetic nervous system and is the leading cause of death among preschool age diseases, so the search for novel therapeutic targets is crucial. Golgi phosphoprotein… read more here.

Keywords: dna damage; damage response; neuroblastoma; damage ... See more keywords

GOLPH3 modulates expression and alternative splicing of transcription factors associated with endometrial decidualization in human endometrial stromal cells

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Published in 2023 at "PeerJ"

DOI: 10.7717/peerj.15048

Abstract: Endometrial decidualization is a decidual tissue formed by the proliferation and re-differentiation of endometrial stroma stimulated by decidualization inducing factors. It is very important for the proper maintenance of pregnancy. Previous studies speculated that Golgi… read more here.

Keywords: endometrial decidualization; golph3; decidualization; alternative splicing ... See more keywords