Redesigned Spider Peptide with Improved Antimicrobial and Anticancer Properties.
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DOI: 10.1021/acschembio.7b00459
Abstract: Gomesin, a disulfide-rich antimicrobial peptide produced by the Brazilian spider Acanthoscurria gomesiana, has been shown to be potent against Gram-negative bacteria and to possess selective anticancer properties against melanoma cells. In a recent study, a… read more here.
Keywords: antimicrobial anticancer; peptide; gomesin; anticancer properties ... See more keywords
Unlocking the Potential of the Antimicrobial Peptide Gomesin: From Discovery and Structure–Activity Relationships to Therapeutic Applications
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DOI: 10.3390/ijms24065893
Abstract: Gomesin is a cationic antimicrobial peptide which is isolated from the haemocytes of the Brazilian tarantula Acanthoscurria gomesiana and can be produced chemically by Fmoc solid-phase peptide synthesis. Gomesin exhibits a range of biological activities,… read more here.
Keywords: structure activity; discovery structure; antimicrobial peptide; gomesin ... See more keywords