Mode et mécanismes de sécrétion des microARN par la cellule gonadotrope hypophysaire
Sign Up to like & getrecommendations! Published in 2018 at "Annales d'Endocrinologie"
DOI: 10.1016/j.ando.2018.06.267
Abstract: Les microARN (miARN) sont des acteurs majeurs dans la regulation des genes et l’expression des phenotypes cellulaires. Ils sont egalement activement secretes et certains sont consideres comme des marqueurs de pathologies. Les miARN circulants peuvent… read more here.
Keywords: gonadotrope; dans des; les miarn; cellule gonadotrope ... See more keywords
Differential roles of PKC isoforms (PKCs) and Ca2+ in GnRH and phorbol 12-myristate 13-acetate (PMA) stimulation of p38MAPK phosphorylation in immortalized gonadotrope cells
Sign Up to like & getrecommendations! Published in 2017 at "Molecular and Cellular Endocrinology"
DOI: 10.1016/j.mce.2016.10.031
Abstract: We examined the role of PKCs and Ca2+ in GnRH-stimulated p38MAPK phosphorylation in the gonadotrope derived αT3-1 and LβT2 cell lines. GnRH induced a slow and rapid increase in p38MAPK phosphorylation in αT3-1 and LβT2… read more here.
Keywords: gonadotrope; pkcs ca2; p38mapk phosphorylation; gnrh ... See more keywords
The Hippo Pathway Effectors YAP and TAZ Regulate LH Release by Pituitary Gonadotrope Cells in Mice.
Sign Up to like & getrecommendations! Published in 2022 at "Endocrinology"
DOI: 10.1210/endocr/bqab238
Abstract: The Hippo transcriptional coactivators YAP and TAZ exert critical roles in morphogenesis, organ size determination and tumorigenesis in many tissues. Although Hippo kinase cascade activity was recently reported in the anterior pituitary gland in mice,… read more here.
Keywords: secretion; yap taz; taz regulate; gonadotrope cells ... See more keywords
HDAC inhibitors impair Fshb subunit expression in murine gonadotrope cells.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of molecular endocrinology"
DOI: 10.1530/jme-18-0145
Abstract: Fertility is dependent on follicle-stimulating hormone (FSH), a product of gonadotrope cells of the anterior pituitary gland. Hypothalamic gonadotropin-releasing hormone (GnRH) and intra-pituitary activins are regarded as the primary drivers of FSH synthesis and secretion.… read more here.
Keywords: expression; gonadotrope; murine gonadotrope; gonadotrope cells ... See more keywords
Intronic Enhancer Is Essential for Nr5a1 Expression in the Pituitary Gonadotrope and for Postnatal Development of Male Reproductive Organs in a Mouse Model
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24010192
Abstract: Nuclear receptor subfamily 5 group A member 1 (NR5A1) is expressed in the pituitary gonadotrope and regulates their differentiation. Although several regulatory regions were implicated in Nr5a1 gene expression in the pituitary gland, none of… read more here.
Keywords: expression pituitary; postnatal development; gonadotrope; pituitary gonadotrope ... See more keywords