Synthesis and biological evaluation of (+)-usnic acid derivatives as potential anti-Toxoplasma gondii agents.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.9b02173
Abstract: Six series of (+)-usnic acid derivatives were synthesized. The IC50 values of these compounds were determined in T. gondii-infected HeLa cells (μM) and in HeLa cells (μM), and their selectivity indexes (SI) were calculated. In… read more here.
Keywords: usnic acid; compound; gondii agents; acid derivatives ... See more keywords
1-hydroxy-7-azabenzotriazole-cinnamic esters as anti-Toxoplasma gondii agents.
Sign Up to like & getrecommendations! Published in 2025 at "Natural product research"
DOI: 10.1080/14786419.2025.2500736
Abstract: The emergence of pharmacological resistance mechanisms coupled with treatment-related toxicities inherent in conventional chemotherapeutic regimens necessitates the development of next-generation targeted therapeutics with enhanced therapeutic indices. It is anticipated that progress in research will aid… read more here.
Keywords: toxoplasma gondii; cinnamic esters; azabenzotriazole cinnamic; hydroxy azabenzotriazole ... See more keywords