Loss of AKR1C1 is a good prognostic factor in advanced NPC cases and increases chemosensitivity to cisplatin in NPC cells
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DOI: 10.1111/jcmm.15291
Abstract: Cisplatin resistance is one of the main obstacles in the treatment of advanced nasopharyngeal carcinoma (NPC). AKR1C1 is a member of the Aldo‐keto reductase superfamily (AKRs), which converts aldehydes and ketones to their corresponding alcohols… read more here.
Keywords: good prognostic; prognostic factor; cisplatin; npc cells ... See more keywords