DNA-Encoded Chemistry: Drug Discovery from a Few Good Reactions.
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DOI: 10.1021/acs.chemrev.0c00789
Abstract: Click chemistry, proposed nearly 20 years ago, promised access to novel chemical space by empowering combinatorial library synthesis with a "few good reactions". These click reactions fulfilled key criteria (broad scope, quantitative yield, abundant starting… read more here.
Keywords: drug discovery; chemistry; good reactions; dna encoded ... See more keywords