Targeting Drosophila Sas6 to mitochondria reveals its high affinity for Gorab
Sign Up to like & getrecommendations! Published in 2022 at "Biology Open"
DOI: 10.1242/bio.059545
Abstract: ABSTRACT The ability to relocalize proteins to defined subcellular locations presents a powerful tool to examine protein-protein interactions that can overcome a tendency of non-targeted exogenous proteins to form inaccessible aggregates. Here, we show that… read more here.
Keywords: sas6 mitochondria; gorab; sas6; drosophila sas6 ... See more keywords
The dimeric Golgi protein Gorab binds to Sas6 as a monomer to mediate centriole duplication
Sign Up to like & getrecommendations! Published in 2021 at "eLife"
DOI: 10.7554/elife.57241
Abstract: The duplication and ninefold symmetry of the Drosophila centriole requires that the cartwheel molecule, Sas6, physically associates with Gorab, a trans-Golgi component. How Gorab achieves these disparate associations is unclear. Here, we use hydrogen–deuterium exchange… read more here.
Keywords: centriole duplication; monomer; gorab; sas6 ... See more keywords