Streptococcus gordonii induces nitric oxide production through its lipoproteins stimulating Toll‐like receptor 2 in murine macrophages
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Immunology"
DOI: 10.1016/j.molimm.2016.12.016
Abstract: HighlightsLipoprotein‐deficient S. gordonii induces less NO production than the wild‐type in macrophages.Lipoprotein‐deficient S. gordonii weakly induces NF‐&kgr;B activation, IFN‐&bgr; expression and STAT1 phosphorylation.Lipoprotein of S. gordonii is a major TLR2 ligand inducing NO production in… read more here.
Keywords: gordonii; production; gordonii wild; dgr ... See more keywords
Enhanced Biofilm Formation of Streptococcus gordonii with Lipoprotein Deficiency.
Sign Up to like & getrecommendations! Published in 2020 at "Molecular oral microbiology"
DOI: 10.1111/omi.12319
Abstract: Streptococcus gordonii is a commensal Gram-positive bacterium that acts as an opportunistic pathogen that can cause apical periodontitis, endocarditis, and pneumonia. Biofilm formation of bacteria is important for the initiation and progression of such diseases.… read more here.
Keywords: wild type; biofilm formation; gordonii; streptococcus gordonii ... See more keywords
Streptococcus gordonii-Induced miRNAs Regulate CCL20 Responses in Human Oral Epithelial Cells
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DOI: 10.1128/iai.00586-21
Abstract: The mechanisms through which oral commensal bacteria mitigates uncontrolled inflammatory responses of the oral mucosa remain unknown. Here, we show that representative oral bacterial species normally associated with oral health [S. gordonii (Sg), V. parvula… read more here.
Keywords: responses oral; gordonii; oral epithelial; epithelial cells ... See more keywords
Uncovering Roles of Streptococcus gordonii SrtA-Processed Proteins in the Biofilm Lifestyle
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Bacteriology"
DOI: 10.1128/jb.00544-20
Abstract: S. gordonii interactions with its environment depend on the complement of cell wall proteins. A subset of these cell wall proteins requires processing by the enzyme sortase A (SrtA). The identification of SrtA-processed proteins and… read more here.
Keywords: srta; processed proteins; srta processed; gordonii ... See more keywords
Impact of Polymicrobial Infection on Fitness of Streptococcus gordonii In Vivo
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DOI: 10.1128/mbio.00658-23
Abstract: Bacteria responsible for diseases originating at oral mucosal membranes assemble into polymicrobial communities. However, we know little regarding the fitness determinants of the organisms that initiate community formation. ABSTRACT Pathogenic microbial ecosystems are often polymicrobial,… read more here.
Keywords: gordonii; streptococcus gordonii; coinfection; fitness ... See more keywords
Spondylodiskitis and endocarditis due to Streptococcus gordonii
Sign Up to like & getrecommendations! Published in 2017 at "Annals of Clinical Microbiology and Antimicrobials"
DOI: 10.1186/s12941-017-0243-8
Abstract: BackgroundStreptococcus gordonii is an infrequent cause of infective endocarditis (IE); associated spondylodiskitis has not yet been described in the literature.PurposeWe describe 2 patients who presented with new-onset, severe back pain; blood cultures revealed S. gordonii… read more here.
Keywords: gordonii bacteremia; spondylodiskitis endocarditis; gordonii; complete cure ... See more keywords
A D-enantiomer of the antimicrobial peptide GL13K evades antimicrobial resistance in the Gram positive bacteria Enterococcus faecalis and Streptococcus gordonii
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DOI: 10.1371/journal.pone.0194900
Abstract: Antimicrobial peptides represent an alternative to traditional antibiotics that may be less susceptible to bacterial resistance mechanisms by directly attacking the bacterial cell membrane. However, bacteria have a variety of defense mechanisms that can prevent… read more here.
Keywords: gram positive; peptide; positive bacteria; gordonii ... See more keywords
The Regulatory Effect of Coaggregation Between Fusobacterium nucleatum and Streptococcus gordonii on the Synergistic Virulence to Human Gingival Epithelial Cells
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2022.879423
Abstract: In subgingival plaque biofilms, Fusobacterium nucleatum is closely related to the occurrence and development of periodontitis. Streptococcus gordonii, as an accessory pathogen, can coaggregate with periodontal pathogens, facilitating the subgingival colonization of periodontal pathogens. Studies… read more here.
Keywords: hgecs; effect coaggregation; gordonii; coinfection ... See more keywords