Gossypin exert lipopolysaccharide induced lung inflammation via alteration of Nrf2/HO-1 and NF-κB signaling pathway.
Sign Up to like & getrecommendations! Published in 2023 at "Environmental toxicology"
DOI: 10.1002/tox.23806
Abstract: Acute Lung Injury (ALI) is a critical medical condition that induces the injury into the lung tissue, resulting in decreased the oxygen levels in the circulation and finally causes the respiratory failure. In this study,… read more here.
Keywords: lung tissue; gossypin; lung; lung inflammation ... See more keywords
Apoptosis-Inducing Activity and Antiproliferative Effect of Gossypin on PC-3 Prostate Cancer Cells.
Sign Up to like & getrecommendations! Published in 2020 at "Anti-cancer agents in medicinal chemistry"
DOI: 10.2174/1871520620666200721103422
Abstract: AIM The rapid growth, morbidity and mortality of prostate cancer, and the lack of effective treatment have attracted great interests of researchers to find novel cancer therapies aiming to the effect of gossypin on cell… read more here.
Keywords: apoptosis; gossypin; prostate cancer; cancer ... See more keywords
Modulation of Liver P-Glycoprotien Expression May Contribute to Gossypin Protection against Methotrexate-Induced Hepatotoxicity
Sign Up to like & getrecommendations! Published in 2021 at "Indian Journal of Pharmacology"
DOI: 10.4103/ijp.ijp_824_19
Abstract: OBJECTIVES: Methotrexate (MTX) is a broadly used anticancer. Its major side effect is hepatotoxicity. Gossypin is a flavonoid has a hepatoprotective effect as well as antitumor property. The study aimed at inspecting the protective effect… read more here.
Keywords: expression; liver glycoprotien; gossypin; mtx ... See more keywords