Effect of topiroxostat in patients with diabetic nephropathy and gout or hyperuricemia: fact or fallacy
Sign Up to like & getrecommendations! Published in 2018 at "Clinical and Experimental Nephrology"
DOI: 10.1007/s10157-018-1540-z
Abstract: To the Editor, We have read the research article “Uric acid-lowering and renoprotective effects of topiroxostat, a selective xanthine oxidoreductase inhibitor, in patients with diabetic nephropathy and hyperuricemia: a randomized, double-blind, placebo-controlled, parallel-group study (UPWARD… read more here.
Keywords: patients diabetic; gout hyperuricemia; nephropathy gout; hyperuricemia ... See more keywords
Aronia melanocarpa ameliorates gout and hyperuricemia in animal models
Sign Up to like & getrecommendations! Published in 2018 at "Food and Agricultural Immunology"
DOI: 10.1080/09540105.2018.1541967
Abstract: ABSTRACT Aronia melanocarpa fruit (AM) strongly suppressed ankle swelling in rats with acute gout and reduced the levels of uric acid and xanthine oxidase (XO) in mice with hyperuricemia. AM reduced the inflammatory cell count… read more here.
Keywords: aronia melanocarpa; gout hyperuricemia; ameliorates gout; hyperuricemia animal ... See more keywords
Consumption of sugar sweetened beverages and dietary fructose in relation to risk of gout and hyperuricemia: a systematic review and meta-analysis
Sign Up to like & getrecommendations! Published in 2018 at "Critical Reviews in Food Science and Nutrition"
DOI: 10.1080/10408398.2018.1503155
Abstract: Abstract Background: Findings on the association of sugar sweetened beverages (SSB) and fructose intakes with gout and hyperuricemia have been conflicting. Objective: We aimed to perform a systematic review and meta-analysis on studies that examined… read more here.
Keywords: gout hyperuricemia; analysis; risk gout; hyperuricemia ... See more keywords
Model Informed Development of SIM0295 in Patients with Gout and Hyperuricemia and Healthy Volunteers Using a Population Pharmacokinetics/ Pharmacodynamics Approach.
Sign Up to like & getrecommendations! Published in 2023 at "Expert opinion on investigational drugs"
DOI: 10.1080/13543784.2023.2212153
Abstract: BACKGROUND SIM0295, a novel inhibitor of human uric acid transporter 1 (hURAT1), is used to treat patients with gout and hyperuricemia. This study aimed to develop population pharmacokinetics and pharmacodynamics (popPK/PD) models of SIM0295 and… read more here.
Keywords: gout hyperuricemia; development; patients gout; population pharmacokinetics ... See more keywords
The prevalence of gout and hyperuricemia in middle-aged and elderly people in Tibet Autonomous Region, China
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DOI: 10.1097/md.0000000000018542
Abstract: Abstract Objective: Gout and hyperuricemia are common public health problem. There has been no epidemiological survey of gout and hyperuricemia in Tibet Autonomous Region, the southwest of China. Therefore, we estimated the prevalence of gout… read more here.
Keywords: gout hyperuricemia; prevalence gout; tibet autonomous; gout ... See more keywords
SAT0405 GOUT AND HYPERURICEMIA IN THE US: PREVALENCE AND TRENDS
Sign Up to like & getrecommendations! Published in 2019 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2019-eular.4438
Abstract: Background: While the prevalence of gout and hyperuricemia is believed to be increasing worldwide, there is little population-based data in the US after 2008. We evaluated the prevalence of gout and hyperuricemia in the US… read more here.
Keywords: gout hyperuricemia; prevalence gout; population; prevalence ... See more keywords