Gout and the risk of incident depression in older adults
Sign Up to like & getrecommendations! Published in 2018 at "Psychiatry Research"
DOI: 10.1016/j.psychres.2018.10.067
Abstract: We used the 5% random Medicare claims from Americans 65 years or older from 2006-2012 to examine the association of gout with the risk of developing incident (new) depression using multivariable-adjusted Cox proportional hazards model,… read more here.
Keywords: depression; risk incident; depression older; gout risk ... See more keywords
Gout and the risk of Alzheimer′s disease: A Mendelian randomization study
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Rheumatic Diseases"
DOI: 10.1111/1756-185x.13548
Abstract: This study aimed to examine whether gout is causally associated with Alzheimer's disease. read more here.
Keywords: gout risk; risk alzheimer; disease mendelian; study ... See more keywords
DNA hypomethylation of a transcription factor binding site within the promoter of a gout risk gene NRBP1 upregulates its expression by inhibition of TFAP2A binding
Sign Up to like & getrecommendations! Published in 2017 at "Clinical Epigenetics"
DOI: 10.1186/s13148-017-0401-z
Abstract: BackgroundGenome-wide association studies (GWASs) have identified dozens of loci associated with gout, but for most cases, the risk genes and the underlying molecular mechanisms contributing to these associations are unknown. This study sought to understand… read more here.
Keywords: risk gene; tfap2a; transcription factor; gout risk ... See more keywords
The Epidemiology and Genetics of Hyperuricemia and Gout across Major Racial Groups: A Literature Review and Population Genetics Secondary Database Analysis
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Personalized Medicine"
DOI: 10.3390/jpm11030231
Abstract: Gout is an inflammatory condition caused by elevated serum urate (SU), a condition known as hyperuricemia (HU). Genetic variations, including single nucleotide polymorphisms (SNPs), can alter the function of urate transporters, leading to differential HU… read more here.
Keywords: genetics; racial groups; epidemiology; gout risk ... See more keywords