Hydrogen Sulfide Gas Amplified ROS Cascade: FeS@GOx Hybrid Nanozyme Designed for Boosting Tumor Chemodynamic Immunotherapy.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202300385
Abstract: Chemodynamic immunotherapy that utilizes catalysts to produce reactive oxygen species (ROS) for killing tumor cells and arousing antitumor immunity, has received considerable attention. However, it is still restricted by low ROS production efficiency and insufficient… read more here.
Keywords: immunotherapy; fes gox; chemodynamic immunotherapy; hybrid nanozyme ... See more keywords
Enzyme‐Engineered Conjugated Polymer Nanoplatform for Activatable Companion Diagnostics and Multistage Augmented Synergistic Therapy
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Materials"
DOI: 10.1002/adma.202200062
Abstract: Companion diagnostics (CDx) provides critical information for precision medicine. However, current CDx is mostly limited to in vitro tests, which cannot accurately evaluate the disease progression and treatment response in real time. To overcome this… read more here.
Keywords: multistage; conjugated polymer; therapy; gox ... See more keywords
Enzyme‐mediated hydrogel encapsulation of single cells for high‐throughput screening and directed evolution of oxidoreductases
Sign Up to like & getrecommendations! Published in 2019 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.27002
Abstract: Directed evolution of oxidoreductases to improve their catalytic properties is being ardently pursued in the industrial, biotechnological, and biopharma sectors. Hampering this pursuit are current enzyme screening methods that are limited in terms of throughput,… read more here.
Keywords: hydrogel; evolution; evolution oxidoreductases; gox ... See more keywords
Dual H2 O2 -Amplified Nanofactory for Simultaneous Self-Enhanced NIR-II Fluorescence Activation Imaging and Synergistic Tumor Therapy.
Sign Up to like & getrecommendations! Published in 2022 at "Small"
DOI: 10.1002/smll.202203531
Abstract: Activatable fluorescence imaging in the second near-infrared window (NIR-II FL, 1000-1700 nm) is of great significance for accurate tumor diagnosis and targeting therapy. However, the clinical translation of most stimulus-activated nanoprobes is severely restricted by insufficient… read more here.
Keywords: dual amplified; therapy; amplified nanofactory; tumor ... See more keywords
Electrochemical glucose biosensor based on ZnO nanorods modified with gold nanoparticles
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Materials Science: Materials in Electronics"
DOI: 10.1007/s10854-019-01059-9
Abstract: Gold nanoparticles (AuNPs) were synthesized by seeded-growth method. Spherical AuNPs with different sizes were formed by varying the volumes of the gold seed, hydroxylamine hydrochloride, and gold chloride. Zinc oxide nanorods (ZnONRs) were also produced… read more here.
Keywords: seed; gold nanoparticles; ito; ito substrates ... See more keywords
Preparation of V2O5/GOx onto a Screen-Printed Electrode for Sensing Surface of Glucose
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Electronic Materials"
DOI: 10.1007/s11664-018-6490-4
Abstract: Glucose oxidase (GOx) was immobilized on vanadium pentoxide xerogel (V2O5) onto a carbon-based screen-printed electrode to evaluate the possibility of constructing a V2O5/GOx biosensor. Structural characterizations of V2O5/GOx demonstrated a weak interaction between the species.… read more here.
Keywords: gox; v2o5 gox; printed electrode; screen printed ... See more keywords
Expression and Characterization of Glucose Oxidase from Aspergillus niger in Yarrowia lipolytica
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Biotechnology"
DOI: 10.1007/s12033-017-0017-8
Abstract: Glucose oxidase (GOX) is currently used in clinical, pharmaceutical, food and chemical industries. The aim of this study was expression and characterization of Aspergillus niger glucose oxidase gene in the yeast Yarrowia lipolytica. For the… read more here.
Keywords: oxidase; expression characterization; glucose oxidase; niger ... See more keywords
Tumor metabolism destruction via metformin-based glycolysis inhibition and glucose oxidase-mediated glucose deprivation for enhanced cancer therapy.
Sign Up to like & getrecommendations! Published in 2022 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2022.04.022
Abstract: Cancer cells rely on glycolysis to support a high proliferation rate. Metformin (Met) is a promising drug for tumor treatment that targets hexokinase 2 (HK2) to block the glycolytic process, thereby further disrupting the metabolism… read more here.
Keywords: therapy; glycolysis inhibition; gox; cancer ... See more keywords
A hybrid biocatalyst consisting of silver nanoparticle and naphthalenethiol self-assembled monolayer prepared for anchoring glucose oxidase and its use for an enzymatic biofuel cell
Sign Up to like & getrecommendations! Published in 2018 at "Applied Surface Science"
DOI: 10.1016/j.apsusc.2017.07.023
Abstract: Abstract A novel hybrid biocatalyst is synthesized by the enzyme composite consisting of silver nanoparticle (AgNP), naphthalene-thiol based couplers (Naph-SH) and glucose oxidase (GOx), which is then bonded with the supporter consisting of polyethyleneimine (PEI)… read more here.
Keywords: glucose oxidase; self assembled; gox; hybrid biocatalyst ... See more keywords
Iridium/ruthenium nanozyme reactors with cascade catalytic ability for synergistic oxidation therapy and starvation therapy in the treatment of breast cancer.
Sign Up to like & getrecommendations! Published in 2020 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2020.119848
Abstract: The application of nanozymes to specifically treat tumors in the tumor microenvironment (TME) would be a novel and effective strategy. Here, ultra-small IrRu alloy nanoparticles (IrRu NPs) with dual enzyme activities were synthesized by a… read more here.
Keywords: starvation therapy; treatment; gox; cancer ... See more keywords
Glucose biofuel cells using bi-enzyme catalysts including glucose oxidase, horseradish peroxidase and terephthalaldehyde crosslinker
Sign Up to like & getrecommendations! Published in 2018 at "Chemical Engineering Journal"
DOI: 10.1016/j.cej.2017.10.121
Abstract: Abstract Biocatalysts consisting of bi-enzyme of glucose oxidase (GOx) and horseradish peroxidase (HRP) and terephthalaldehyde (TPA) as cross-linker ([(TPA/HRP/GOx)]/PEI/CNT) that have different GOx and HRP mass ratio are developed and their catalytic activity about glucose… read more here.
Keywords: tpa hrp; glucose oxidase; hrp gox; gox ... See more keywords