Articles with "gp130 mediated" as a keyword



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O39 Gp130-mediated STAT3 activation by S-propargyl-cysteine, an endogenous hydrogen sulfide initiator, prevents doxorubicin-induced cardiotoxicity

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Published in 2017 at "Biochemical Pharmacology"

DOI: 10.1016/j.bcp.2017.06.104

Abstract: Doxorubicin (Dox) could trigger a large amount of apoptotic cells in the myocardium, which leads to dilated cardiomyopathy and heart failure. S-propargyl-cysteine (SPRC), an endogenous hydrogen sulfide (H 2 S) initiator, possesses cardioprotective efficacy. However,… read more here.

Keywords: induced cardiotoxicity; propargyl cysteine; gp130 mediated; cardiotoxicity ... See more keywords