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Published in 2019 at "Heliyon"
DOI: 10.1016/j.heliyon.2019.e03018
Abstract: Fusion of host and viral membranes is a crucial step during infection by enveloped viruses. In the structurally-defined “class I″ viral glycoproteins, the formation of a highly stable α-helical bundle by the ectodomain of the…
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Keywords:
marburg virus;
gp2;
membrane proximal;
fusion ... See more keywords
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Published in 2022 at "Stem cell reports"
DOI: 10.1016/j.stemcr.2022.03.004
Abstract: Human pluripotent stem cell (hPSC)-derived pancreatic progenitors (PPs) can be differentiated into beta-like cells in vitro and in vivo and therefore have therapeutic potential for type 1 diabetes (T1D) treatment. However, the purity of PPs varies across…
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Keywords:
gp2 enriched;
gp2;
pancreatic progenitors;
give rise ... See more keywords
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Published in 2017 at "Tuberculosis"
DOI: 10.1016/j.tube.2017.07.004
Abstract: Over the past six decades, there has been a decline in novel therapies to treat tuberculosis, while the causative agent of this disease has become increasingly resistant to current treatment regimens. Bacteriophages (phages) are able…
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Keywords:
protein;
exploring potential;
gp2;
rna polymerase ... See more keywords
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Published in 2018 at "Bioconjugate chemistry"
DOI: 10.1021/acs.bioconjchem.8b00144
Abstract: The Gp2 domain is a protein scaffold for synthetic ligand engineering. However, the native protein function results in a heterogeneous distribution of charge on the conserved surface, which may hinder further development and utility. We…
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Keywords:
gp2;
charge;
factor receptor;
growth factor ... See more keywords
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Published in 2018 at "Proceedings of the Institution of Mechanical Engineers, Part D: Journal of Automobile Engineering"
DOI: 10.1177/0954407017728158
Abstract: In this work, optimal control theory is applied to minimum lap time simulation of a GP2 car, using a multibody car model with enhanced load transfer dynamics. The mathematical multibody model is formulated with use…
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Keywords:
gp2;
time;
simulation;
car ... See more keywords
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Published in 2021 at "Microbial Cell Factories"
DOI: 10.1186/s12934-021-01512-7
Abstract: Background Precise regulation of gene expression is of utmost importance for the production of complex membrane proteins (MP), enzymes or other proteins toxic to the host cell. In this article we show that genes under…
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Keywords:
production;
gp2;
system;
expression ... See more keywords
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Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0185099
Abstract: One of the challenging issues in vaccine development is peptide and adjuvant delivery into target cells. In this study, we developed a vaccine and therapeutic delivery system to increase cytotoxic T lymphocyte (CTL) response against…
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Keywords:
dope;
her2 neu;
gp2;
dope mpl ... See more keywords
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Published in 2021 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2021.685524
Abstract: Background Recently, NUS1 and GP2 genes were reported to be associated with the risk of type 2 diabetes (T2D) in a Japanese population. Given the sharing of pathogenic contribution from genetic factors between T2D and…
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Keywords:
gestational diabetes;
risk;
nus1 gp2;
gp2 ... See more keywords
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Published in 2018 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2018.01959
Abstract: Introduction: Zymogen granule glycoprotein 2 (GP2) was demonstrated as first autoimmune mucosal target in primary sclerosing cholangitis (PSC) associated with disease severity. Autoantibodies to four GP2 isoforms (aGP21−4) were found in patients with inflammatory bowel…
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Keywords:
gp2;
psc associated;
agp24 iga;
gp2 isoforms ... See more keywords