Development of a DNA vaccine expressing a secreted HIV-1 gp41 ectodomain that includes the membrane-proximal external region.
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DOI: 10.1016/j.vaccine.2017.03.039
Abstract: A limited number of sites on the HIV-1 Envelope protein are vulnerable to broadly neutralizing antibodies (bnAbs). One of these sites, the membrane proximal external region (MPER), is located at the C-terminus of the gp41… read more here.
Keywords: membrane proximal; gp41; proximal external; gp41 ectodomain ... See more keywords