Tumor Microenvironment Regulation by the Endoplasmic Reticulum Stress Transmission Mediator Golgi Protein 73 in Mice
Sign Up to like & getrecommendations! Published in 2019 at "Hepatology"
DOI: 10.1002/hep.30549
Abstract: The unfolded protein response (UPR) signal in tumor cells activates UPR signaling in neighboring macrophages, which leads to tumor‐promoting inflammation by up‐regulating UPR target genes and proinflammatory cytokines. However, the molecular basis of this endoplasmic… read more here.
Keywords: protein; gp73; stress; stress transmission ... See more keywords
GP73 facilitates hepatitis B virus replication by repressing the NF‐κB signaling pathway
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Medical Virology"
DOI: 10.1002/jmv.25718
Abstract: Hepatitis B virus (HBV) chronically infects approximately 350 million people worldwide, and 600 000 deaths are caused by HBV‐related hepatic failure. Golgi protein 73 (GP73) is a serum biomarker for liver diseases, including chronic hepatitis B.… read more here.
Keywords: gp73; hbv replication; gp73 facilitates; hepatitis virus ... See more keywords
Ratiometric Immunosensor for GP73 Detection Based on the Ratios of Electrochemiluminescence and Electrochemical Signal Using DNA Tetrahedral Nanostructure as the Carrier of Stable Reference Signal.
Sign Up to like & getrecommendations! Published in 2019 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.9b00013
Abstract: DNA tetrahedron nanostructure (DTNs) has the merits of simple synthesis, high yield, structural stability, and mechanical rigidity, and its three-dimensional structure provides a satisfactory biosensing interface to the improvement of the binding efficiency of antigenic… read more here.
Keywords: electrochemistry; ratiometric immunosensor; gp73; reference signal ... See more keywords
The potential value of serum GP73 in the ancillary diagnosis and grading of liver cirrhosis
Sign Up to like & getrecommendations! Published in 2023 at "Scandinavian Journal of Clinical and Laboratory Investigation"
DOI: 10.1080/00365513.2023.2175238
Abstract: Abstract This study is to evaluate the potential value of serum GP73 in ancillary cirrhosis diagnosis. 150 cirrhotic subjects and healthy subjects were retrospectively analyzed, and the two groups were compared in terms of Child‒Pugh… read more here.
Keywords: diagnosis; gp73; value; cirrhosis ... See more keywords
GP73 promotes epithelial–mesenchymal transition and invasion partly by activating TGF-&bgr;1/Smad2 signaling in hepatocellular carcinoma
Sign Up to like & getrecommendations! Published in 2018 at "Carcinogenesis"
DOI: 10.1093/carcin/bgy010
Abstract: The transforming growth factor-β1 (TGF-β1) signaling pathways contribute to cell metastasis and epithelial-mesenchymal transition (EMT). Golgi protein 73 (GP73), a type II transmembrane protein in the Golgi apparatus, was initially regarded as a potential biomarker… read more here.
Keywords: hcc; invasion; gp73; metastasis ... See more keywords
The Value of MRI Combined with AFP, AFP-L3, GP73, and DCP in the Diagnosis of Early Primary Liver Cancer
Sign Up to like & getrecommendations! Published in 2022 at "Disease Markers"
DOI: 10.1155/2022/8640999
Abstract: Objective To investigate the diagnostic value of magnetic resonance imaging (MRI) combined with serum alpha-fetoprotein (AFP), alpha-fetoprotein (AFP-L3), Golgi protein 73 (GP73), and des-γ-carboxyprothrombin (DCP) on early-stage primary liver cancer (PHC). Methods A total of… read more here.
Keywords: group; gp73; afp afp; control group ... See more keywords
Fluorescent "turn-on" aptamer sensor for sensitive and reliable detection of Golgi glycoprotein 73 based on nitrogen-doped graphene quantum dots and molybdenum disulfide nanosheets.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of pharmaceutical and biomedical analysis"
DOI: 10.2139/ssrn.4272768
Abstract: The sensitivity and specificity of Golgi glycoprotein 73 (GP73) are very important for early diagnosis of hepatocellular carcinoma. Herein, we constructed a new-fashioned fluorescent aptamer sensor for GP73 determination based on nitrogen-doped graphene quantum dots… read more here.
Keywords: gqds gp73apt; aptamer sensor; gp73; detection ... See more keywords