Genetic variation in the mitochondrial glycerol-3-phosphate acyltransferase is associated with liver injury.
Sign Up to like & getrecommendations! Published in 2021 at "Hepatology"
DOI: 10.1002/hep.32038
Abstract: Most of the genetic basis of chronic liver disease remains undiscovered. To identify novel genetic loci that modulate the risk of liver injury, we performed genome-wide association studies (GWAS) on circulating levels of alanine aminotransferase… read more here.
Keywords: liver injury; liver disease; gpam; mitochondrial glycerol ... See more keywords
Bovine lipid metabolism related gene GPAM: Molecular characterization, function identification, and association analysis with fat deposition traits.
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DOI: 10.1016/j.gene.2017.01.031
Abstract: Glycerol-3-phosphate acyltransferase mitochondrial (GPAM) is the enzyme that catalyzes the initial and committed step of glycerolipid synthesis in animal lipometabolism related pathway. In the present study, the correlation of GPAM expression level with adipogenesis was… read more here.
Keywords: related gene; metabolism related; gpam; expression ... See more keywords
Lnc-PKD2-2-3/miR-328/GPAM ceRNA Network Induces Cholangiocarcinoma Proliferation, Invasion and 5-FU Chemoresistance
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.871281
Abstract: Purpose Our previous study observed that long non-coding RNA PKD2-2-3 (lnc-PKD2-2-3) is related to advanced tumor features and worse prognosis in cholangiocarcinoma (CCA). Then, this study aimed to further explore the linkage between lnc-PKD2-2-3, miR-328,… read more here.
Keywords: lnc pkd2; cca; proliferation; mir 328 ... See more keywords