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   Articles with "gpc" as a keyword



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The Role of Glypican-1 in the Tumour Microenvironment.

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recommendations! Published in 2020 at "Advances in experimental medicine and biology"

DOI: 10.1007/978-3-030-40146-7_8

Abstract: Glypican-1 (GPC-1) is a cell surface heparan sulphate proteoglycan that is critical during normal development, but which is not required for normal homoeostasis in the adult. It is, however, overexpressed in a variety of solid… read more here.

Keywords: role; tumour microenvironment; biology; gpc ... See more keywords

Validation of the effects of the Gpc-B1 high grain protein concentration locus from Lillian hard red spring wheat (Triticum aestivum L.) using locus specific markers

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recommendations! Published in 2018 at "Euphytica"

DOI: 10.1007/s10681-018-2322-0

Abstract: Wheat grain protein concentration (GPC) is negatively associated with economic grain yield (GY) hindering attempts to improve these traits simultaneously. Studies indicate the incorporation of the Gpc-B1 high grain protein gene from emmer wheat into… read more here.

Keywords: grain protein; wheat; protein concentration; gpc ... See more keywords

Triose phosphate utilization determines the Yield-Grain protein trade-off in contrasting rice genotypes under varying light intensities

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recommendations! Published in 2024 at "Plant and Soil"

DOI: 10.1007/s11104-024-06551-8

Abstract: Attempts to increase grain protein content (GPC) most often result in a reduction in yield in cereals. This trade-off between GPC and yield could arise mainly because of the shared source of reductants for carbon… read more here.

Keywords: grain protein; carbon nitrogen; assimilation; utilization ... See more keywords

Convergent Structures Illuminate Features for Germline Antibody Binding and Pan-Lassa Virus Neutralization

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recommendations! Published in 2019 at "Cell"

DOI: 10.1016/j.cell.2019.07.020

Abstract: Lassa virus (LASV) causes hemorrhagic fever and is endemic in West Africa. Protective antibody responses primarily target the LASV surface glycoprotein (GPC), and GPC-B competition group antibodies often show potent neutralizing activity in humans. However,… read more here.

Keywords: antibody; convergent structures; neutralization; gpc ... See more keywords

Estimating genetic variation and genetic parameters for grain iron, zinc and protein concentrations in bread wheat genotypes grown in Iran

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recommendations! Published in 2018 at "Journal of Cereal Science"

DOI: 10.1016/j.jcs.2018.01.009

Abstract: Abstract The low grain micronutrient concentrations particularly iron and zinc are well documented problems in wheat. Eighty bread wheat genotypes were assessed for grain iron (GFeC), zinc (GZnC) and protein (GPC) concentrations along with agronomic… read more here.

Keywords: wheat genotypes; zinc; iron zinc; gpc ... See more keywords

Exposure of carbendazim induces structural and functional alteration in garlic phytocystatin: An in vitro multi-spectroscopic approach.

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recommendations! Published in 2018 at "Pesticide biochemistry and physiology"

DOI: 10.1016/j.pestbp.2018.01.008

Abstract: Carbendazim is a broad spectrum benzimidazole fungicide which is used to ensure plants' protection from pest and pathogens' invasion. The present work describes the impact of carbendazim (CAR) on garlic phytocystatin (GPC) which is a… read more here.

Keywords: carbendazim; alteration; structural functional; gpc ... See more keywords

Structure-guided design of a prefusion GPC trimer induces neutralizing responses against LASV

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recommendations! Published in 2025 at "NPJ Vaccines"

DOI: 10.1038/s41541-025-01090-4

Abstract: Lassa virus (LASV) belongs to the Arenaviridae family and causes severe hemorrhagic fever in humans. Although many vaccine candidates for Lassa fever exist, no vaccines have been approved for clinical use currently. The precursor glycoprotein… read more here.

Keywords: gpcv2; prefusion; gpc trimer; prefusion gpc ... See more keywords

Durability characteristics of geopolymer concrete produced using gold ore tailings along with recycled coarse aggregates

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recommendations! Published in 2025 at "Scientific Reports"

DOI: 10.1038/s41598-025-97056-6

Abstract: The Gold Ore Tailings (GOTs) are one of the major waste materials in the mining sector. The disposal of these tailings could be a problem for human health and a major environmental concern for several… read more here.

Keywords: gpc samples; ore tailings; geopolymer concrete; gold ore ... See more keywords

Mass-resolved UV-Vis-GPC mapping diagnoses catalyst ageing in RCF lignin streams.

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recommendations! Published in 2025 at "Faraday discussions"

DOI: 10.1039/d5fd00109a

Abstract: Catalyst stability is central to the viability of lignin-first biorefineries, yet conventional characterisation often fails to detect the subtle deactivation processes that govern product quality. Here, we demonstrate that ultraviolet-visible (UV-Vis) spectroscopy, when combined with… read more here.

Keywords: spectroscopy; catalyst; catalyst ageing; si320 ... See more keywords

Clinical development of an anti-GPC-1 antibody for the treatment of cancer

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recommendations! Published in 2022 at "Expert Opinion on Biological Therapy"

DOI: 10.1080/14712598.2022.2033204

Abstract: ABSTRACT Introduction Glypican-1 (GPC-1) is a heparan sulfate proteoglycan (HSPG) overexpressed in multiple cancers. Multiple studies indicate the prominence of this cancer biomarker with significant diagnostic and therapeutic potential. Recent advances in monoclonal antibody (mAb)-based… read more here.

Keywords: anti gpc; gpc; gpc antibody; clinical development ... See more keywords

PSIV-A-12 Ruminal in vitro digestibility of novel pennycress meal using the Daisy II incubator

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recommendations! Published in 2024 at "Journal of Animal Science"

DOI: 10.1093/jas/skae102.417

Abstract: Field pennycress seed has a high oil content, making it valuable for biofuel production. The high protein content of the resulting pennycress meal makes it a potentially valuable protein feedstuff for livestock. However, pennycress meal… read more here.

Keywords: digestibility; novel pennycress; pennycress meal; pennycress ... See more keywords