Glypican-3-specific cytotoxic T lymphocytes induced by human leucocyte antigen-A*0201-restricted peptide effectively kill hepatocellular carcinoma cells in vitro.
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DOI: 10.1016/j.apjtm.2017.10.013
Abstract: OBJECTIVE To investigate potential human leucocyte antigen (HLA)-A2-restricted epitope peptides of glypican-3 (GPC3) and determine the cytotoxicity of peptide-specific cytotoxic T lymphocytes (CTLs) against hepatocellular carcinoma (HCC) cells. METHODS The potential HLA-A*0201-restricted GPC3 peptides were… read more here.
Keywords: peptide; human leucocyte; gpc3 522; hla ... See more keywords