Structural and functional impact of post-translation modification of GPC3 on liver carcinogenesis.
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DOI: 10.1158/0008-5472.can-22-3895
Abstract: Glypican-3 (GPC3) is a cell-surface glycoprotein that is frequently overexpressed in hepatocellular carcinoma. GPC3 undergoes extensive post-translational modification including cleavage and glycosylation. This review focuses on the structure and function of GPC3 in liver cancer,… read more here.
Keywords: modification; gpc3; post translation; gpc3 liver ... See more keywords