In situ visualization of opioid and cannabinoid drug effects using phosphosite-specific GPCR antibodies
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DOI: 10.1101/2022.06.14.496067
Abstract: Phosphorylation of receptors is shown to be unstable during routine immunohistochemical procedures in mice thus phosphatase inhibitors should be used alongside phosphosite-specific GPCR antibodies. G protein-coupled receptors (GPCRs) are important signal transducers that are phosphorylated… read more here.
Keywords: phosphosite specific; mop; gpcr antibodies; specific gpcr ... See more keywords
Antigen Design for Successful Isolation of Highly Challenging Therapeutic Anti-GPCR Antibodies
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DOI: 10.3390/ijms21218240
Abstract: G-protein-coupled receptors (GPCR) transmit extracellular signals into cells to regulate a variety of cellular functions and are closely related to the homeostasis of the human body and the progression of various types of diseases. Great… read more here.
Keywords: therapeutic anti; antigen design; gpcr antibodies; anti gpcr ... See more keywords