Combinatorial expression of GPCR isoforms affects signalling and drug responses
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DOI: 10.1038/s41586-020-2888-2
Abstract: G-protein-coupled receptors (GPCRs) are membrane proteins that modulate physiology across human tissues in response to extracellular signals. GPCR-mediated signalling can differ because of changes in the sequence 1 , 2 or expression 3 of the… read more here.
Keywords: drug responses; combinatorial expression; gpcr isoforms; gpcr ... See more keywords