GPCRs and Signal Transducers: Interaction Stoichiometry.
Sign Up to like & getrecommendations! Published in 2018 at "Trends in pharmacological sciences"
DOI: 10.1016/j.tips.2018.04.002
Abstract: Until the late 1990s, class A G protein-coupled receptors (GPCRs) were believed to function as monomers. Indirect evidence that they might internalize or even signal as dimers has emerged, along with proof that class C… read more here.
Keywords: gpcrs signal; interaction stoichiometry; class; signal transducers ... See more keywords
Another way for GPCRs to signal
Sign Up to like & getrecommendations! Published in 2021 at "Science"
DOI: 10.1126/science.371.6534.1117-m
Abstract: Signal Transduction G protein–coupled receptors (GPCRs) normally transmit signals by coupling to heterotrimeric guanine nucleotide–binding proteins (G proteins) or by binding β-arrestin proteins. Smith et al. provide evidence for another mechanism, an approximate combination of… read more here.
Keywords: another way; signal; way gpcrs; gpcrs signal ... See more keywords