Parkinsonism in GPi‐DBS for Dystonia; When to Suspect Degenerative Parkinsonism?
Sign Up to like & getrecommendations! Published in 2022 at "Movement Disorders Clinical Practice"
DOI: 10.1002/mdc3.13552
Abstract: Bilateral GPi-DBS is an established treatment for refractory dystonia. 1 Stimulation-induced parkinsonism is a frequent and often disabling side effect of GPi-DBS. 2 This parkinsonism mainly constitutes of bradykinesia and axial motor signs, and can… read more here.
Keywords: parkinsonism gpi; gpi dbs; parkinsonism; dystonia ... See more keywords
Globus Pallidus Internus (GPi) Deep Brain Stimulation for Parkinson’s Disease: Expert Review and Commentary
Sign Up to like & getrecommendations! Published in 2020 at "Neurology and Therapy"
DOI: 10.1007/s40120-020-00220-5
Abstract: The globus pallidus internus (GPi) region has evolved as a potential target for deep brain stimulation (DBS) in Parkinson’s disease (PD). DBS of the GPi (GPi DBS) is an established, safe and effective method for… read more here.
Keywords: globus pallidus; disease; target; gpi dbs ... See more keywords
An individual patient analysis of the efficacy of using GPi-DBS to treat Huntington’s disease
Sign Up to like & getrecommendations! Published in 2020 at "Brain Stimulation"
DOI: 10.1016/j.brs.2020.09.025
Abstract: OBJECTIVE The efficacy of globus pallidus internus-deep brain stimulation (GPi-DBS) for the treatment of Huntington's disease (HD) has not been validated in large-scale studies. We conducted an individual patient analysis to pool outcomes of all… read more here.
Keywords: huntington disease; gpi dbs; dbs; motor ... See more keywords
F151. Sensorimotor cortex plasticity correlates with effectiveness of pallidal stimulation in dystonia
Sign Up to like & getrecommendations! Published in 2018 at "Clinical Neurophysiology"
DOI: 10.1016/j.clinph.2018.04.314
Abstract: Introduction Deep brain stimulation (DBS) of the globus pallidus interna (GPi) is an effective symptomatic treatment of farmacoresistant dystonic syndromes. The sensorimotor cortex of dystonia patients exhibits an exaggerated responsiveness to the TMS (transcranial magnetic… read more here.
Keywords: stimulation; dystonia; sensorimotor cortex; gpi dbs ... See more keywords
Intermuscular coherence as biomarker for pallidal deep brain stimulation efficacy in dystonia
Sign Up to like & getrecommendations! Published in 2019 at "Clinical Neurophysiology"
DOI: 10.1016/j.clinph.2019.04.717
Abstract: OBJECTIVE Finding a non-invasive biomarker for Globus Pallidus interna Deep Brain Stimulation (GPi-DBS) efficacy. Dystonia heterogeneity leads to a wide variety of clinical response to GPi-DBS, making it hard to predict GPi-DBS efficacy for individual… read more here.
Keywords: stimulation; biomarker; efficacy; gpi dbs ... See more keywords
Apathy following Bilateral Deep Brain Stimulation of Subthalamic Nucleus and Globus Pallidus Internus in Parkinson's Disease: A Meta-Analysis
Sign Up to like & getrecommendations! Published in 2022 at "Parkinson's Disease"
DOI: 10.1155/2022/4204564
Abstract: Parkinson's disease (PD) is a progressive neurodegenerative disorder typically manifested by its motor symptoms. In addition, PD patients also suffer from many nonmotor symptoms (NMSs), such as apathy. Bilateral deep brain stimulation (DBS) of the… read more here.
Keywords: dbs; parkinson disease; gpi dbs; stn dbs ... See more keywords
BOLD frequency-dependent alterations in resting-state functional connectivity by pallidal deep brain stimulation in patients with Parkinson's disease.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of neurosurgery"
DOI: 10.3171/2023.1.jns221858
Abstract: OBJECTIVE Functional MRI (fMRI) has been used to investigate the therapeutic mechanisms underlying deep brain stimulation (DBS) for Parkinson's disease (PD). However, the alterations in stimulation site-seeded functional connectivity induced by DBS at the internal… read more here.
Keywords: connectivity; gpi dbs; motor; stimulation ... See more keywords
Pallidal Deep Brain Stimulation for Monogenic Dystonia: The Effect of Gene on Outcome
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Neurology"
DOI: 10.3389/fneur.2020.630391
Abstract: Globus pallidus internus deep brain stimulation (GPi DBS) is the most effective intervention for medically refractory segmental and generalized dystonia in both children and adults. Predictive factors for the degree of improvement after GPi DBS… read more here.
Keywords: stimulation; dystonia; gpi dbs; dbs ... See more keywords
GPi DBS treatment outcome in children with monogenic dystonia: a case series and review of the literature
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Neurology"
DOI: 10.3389/fneur.2023.1151900
Abstract: Introduction Dystonia is the third most common pediatric movement disorder and is often difficult to treat. Deep brain stimulation (DBS) of the internal pallidum (GPi) has been demonstrated as a safe and effective treatment for… read more here.
Keywords: case series; gpi dbs; monogenic dystonia; dystonia ... See more keywords
Unilateral GPi-DBS Improves Ipsilateral and Axial Motor Symptoms in Parkinson’s Disease as Evidenced by a Brain Perfusion Single Photon Emission Computed Tomography Study
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Human Neuroscience"
DOI: 10.3389/fnhum.2022.888701
Abstract: Introduction Deep brain stimulation (DBS) is an effective treatment for advanced Parkinson’s disease (PD) with the targeting bilateral subthalamic nucleus or globus pallidus internus (STN or GPi-DBS). So far, detailed studies on the efficacy of… read more here.
Keywords: dbs; motor symptoms; parkinson disease; gpi dbs ... See more keywords