Somatic mutations and clonal expansions in paroxysmal nocturnal hemoglobinuria.
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DOI: 10.1053/j.seminhematol.2022.08.004
Abstract: Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired clonal hematopoietic stem cell disorder caused by a mutation of the X-linked PIGA gene, resulting in a deficient expression of glycosylphosphatidylinositol (GPI)-anchored proteins. While large clonal expansions of… read more here.
Keywords: gpi; gpi hspcs; nocturnal hemoglobinuria; paroxysmal nocturnal ... See more keywords