The impact of aberrant von Willebrand factor-GPIbα interaction on megakaryopoiesis and platelets in humanized type 2B von Willebrand disease model mouse
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DOI: 10.3324/haematol.2021.280561
Abstract: Type 2B von Willebrand disease (VWD) is caused by gain-of-function mutations in von Willebrand factor (VWF). Increased VWF affinity for GPIbα results in loss of high molecular weight multimers and enhanced platelet clearance, both contributing… read more here.
Keywords: gpib interaction; willebrand; von willebrand; type vwd ... See more keywords