A-123 Nascent ADAM17 synthesis potentiates GPIba cleavage in resting and stimulated stored platelets
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DOI: 10.1093/clinchem/hvaf086.119
Abstract: Platelet concentrates stored at room temperature have a shelf life of five days. During storage, platelets undergo glycoprotein cleavage by metalloproteases, notably ADAM17 cleavage of GPIba, which leads to decreased post-transfusion reactivity and recovery. Aim:… read more here.
Keywords: stored platelets; adam17 synthesis; storage; gpiba ... See more keywords