Investigation of redox modifications of platelet integrin GPIIb-IIIa in diabetes
Sign Up to like & getrecommendations! Published in 2018 at "Free Radical Biology and Medicine"
DOI: 10.1016/j.freeradbiomed.2018.10.102
Abstract: Diabetes is a global health problem, affecting 382 million people worldwide. Critically, up to 70% of deaths from diabetes are due to the development of occlusive blood clots (thrombosis), leading to heart attack and stroke.… read more here.
Keywords: iiia diabetes; gpiib; integrin gpiib; gpiib iiia ... See more keywords
Mechanosensing via a GpIIb/Src/14-3-3ΞΆ axis critically regulates platelet migration in vascular inflammation.
Sign Up to like & getrecommendations! Published in 2023 at "Blood"
DOI: 10.1182/blood.2022019210
Abstract: Platelets are first responders in thrombosis and hemostasis, but also central players in inflammation. Compared to platelets recruited to thrombi, immune-responsive platelets use distinct effector functions including Arp2/3-dependent migration along adhesive substrate gradients (haptotaxis), which… read more here.
Keywords: inflammation; platelet migration; migration; gpiib ... See more keywords