Cap‐independent translation of GPLD1 enhances markers of brain health in long‐lived mutant and drug‐treated mice
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DOI: 10.1111/acel.13685
Abstract: Glycosylphosphatidylinositol‐specific phospholipase D1 (GPLD1) hydrolyzes inositol phosphate linkages in proteins anchored to the cell membrane. Mice overexpressing GPLD1 show enhanced neurogenesis and cognition. Snell dwarf (DW) and growth hormone receptor knockout (GKO) mice show delays… read more here.
Keywords: cap independent; brain; independent translation; gpld1 ... See more keywords