Is GPNMB the Achilles' Heel of Mo-MDSC While Marking Their Suppressive Activity?
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DOI: 10.1158/1078-0432.ccr-18-2334
Abstract: Glycoprotein nonmetastatic B/DC-Hil/Osteoactivin on myeloid-derived suppressor cells impairs T lymphocytes through the binding of Syndecan-4, delineating a new checkpoint pair to be targeted perhaps in combination with PD-1/PD-L1 blockage. See related article by Kobayashi et… read more here.
Keywords: gpnmb achilles; suppressive activity; heel mdsc; achilles heel ... See more keywords