Ligand-binding and -scavenging of the chemerin receptor GPR1
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DOI: 10.1007/s00018-021-03894-8
Abstract: Graphic abstract Tight regulation of cytokines is essential for the initiation and resolution of inflammation. Chemerin, a mediator of innate immunity, mainly acts on chemokine-like receptor 1 (CMKLR1) to induce the migration of macrophages and… read more here.
Keywords: receptor gpr1; ligand binding; chemerin receptor; gpr1 ... See more keywords
An Antagonistic Peptide of Gpr1 Ameliorates LPS-Induced Depression through the Hypothalamic-Pituitary-Ovarian Axis
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DOI: 10.3390/biom11060857
Abstract: Depression affects the reproductive axis at the hypothalamus and pituitary levels, which has a significant impact on female fertility. It has been reported that G protein-coupled receptor 1 (Gpr1) mRNA is expressed in both the… read more here.
Keywords: depression; axis; antagonistic peptide; gpr1 ... See more keywords