Expression Analysis of Fibronectin Type III Domain-Containing (FNDC) Genes in Inflammatory Bowel Disease and Colorectal Cancer
Sign Up to like & getrecommendations! Published in 2019 at "Gastroenterology Research and Practice"
DOI: 10.1155/2019/3784172
Abstract: Background Fibronectin type III domain-containing (FNDC) proteins fulfill manifold functions in tissue development and regulation of cellular metabolism. FNDC4 was described as anti-inflammatory factor, upregulated in inflammatory bowel disease (IBD). FNDC signaling includes direct cell-cell… read more here.
Keywords: fndc4; fibronectin type; gpr116; expression ... See more keywords
Regulation of pulmonary surfactant by the adhesion GPCR GPR116/ADGRF5 requires a tethered agonist-mediated activation mechanism
Sign Up to like & getrecommendations! Published in 2022 at "eLife"
DOI: 10.7554/elife.69061
Abstract: The mechanistic details of the tethered agonist mode of activation for the adhesion GPCR ADGRF5/GPR116 have not been completely deciphered. We set out to investigate the physiological importance of autocatalytic cleavage upstream of the agonistic… read more here.
Keywords: agonist mediated; tethered agonist; adhesion gpcr; gpr116 ... See more keywords