Articles with "gpr119 agonist" as a keyword



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GPR119 agonists: Novel therapeutic agents for type 2 diabetes mellitus.

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Published in 2021 at "Bioorganic chemistry"

DOI: 10.1016/j.bioorg.2021.104998

Abstract: Diabetes mellitus type 2 (T2D) is a group of genetically heterogeneous metabolic disorders whose frequency has gradually risen worldwide. Diabetes mellitus Type 2 (T2D) has started to achieve a pandemic level, and it is estimated… read more here.

Keywords: gpr119 agonists; type diabetes; gpr119 agonist; diabetes mellitus ... See more keywords
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Chemistry and Hypoglycemic Activity of GPR119 Agonist ZB-16

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Published in 2018 at "Frontiers in Endocrinology"

DOI: 10.3389/fendo.2018.00543

Abstract: This article is to highlight the chemical properties and primary pharmacology of novel GPR119 agonist ZB-16 and its analogs, which were rejected during the screening. Experiments were performed in vitro (specific activity, metabolism and cell… read more here.

Keywords: activity gpr119; chemistry; gpr119 agonist; chemistry hypoglycemic ... See more keywords