Cannabidiol, a novel inverse agonist for GPR12.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.09.001
Abstract: GPR12 is a constitutively active, Gs protein-coupled receptor that currently has no confirmed endogenous ligands. GPR12 may be involved in physiological processes such as maintenance of oocyte meiotic arrest and brain development, as well as… read more here.
Keywords: inverse agonist; cbd; agonist gpr12; cancer ... See more keywords
Advances in Neurobiology and Pharmacology of GPR12
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2020.00628
Abstract: GPR12 is a G protein-coupled orphan receptor genetically related to type 1 and type 2 cannabinoid receptors (CB1 and CB2) which are ancient proteins expressed all over the body. Both cannabinoid receptors, but especially CB1,… read more here.
Keywords: advances neurobiology; pharmacology; pharmacology gpr12; gpr12 ... See more keywords