Articles with "gpr143" as a keyword



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Immunoreactivity of a G protein-coupled l-DOPA receptor GPR143, in Lewy bodies

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Published in 2019 at "Neuroscience Research"

DOI: 10.1016/j.neures.2018.12.004

Abstract: l-3,4-Dihydroxyphenylalanine (l-DOPA) has been believed to be an inert amino acid precursor of dopamine, and is the most effective therapeutic agent in Parkinson's disease (PD). We proposed l-DOPA as a neurotransmitter in the central nervous… read more here.

Keywords: lewy bodies; immunoreactivity protein; gpr143 immunoreactive; receptor ... See more keywords
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L-DOPA-Induced Neurogenesis in the Hippocampus Is Mediated through GPR143, a Distinct Mechanism of Dopamine.

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Published in 2022 at "Stem cells"

DOI: 10.1093/stmcls/sxab013

Abstract: Neurogenesis occurs in the hippocampus throughout life and is implicated in various physiological brain functions such as memory encoding and mood regulation. L-3,4-dihydroxyphenylalanine (L-DOPA) has long been believed to be an inert precursor of dopamine.… read more here.

Keywords: dopamine; dopa induced; hippocampus; neurogenesis ... See more keywords
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Identification of a novel GPR143 mutation in a large Chinese family with isolated foveal hypoplasia

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Published in 2021 at "BMC Ophthalmology"

DOI: 10.1186/s12886-021-01905-7

Abstract: Background Pathogenic variants of G-protein coupled receptor 143 (GPR143) gene often leads to ocular albinism type I (OA1) characterized by nystagmus, iris and fundus hypopigmentation, and foveal hypoplasia. In this study, we identified a novel… read more here.

Keywords: large chinese; family; foveal hypoplasia; gpr143 ... See more keywords