Legitimizing a chemoattractant receptor
Sign Up to like & getrecommendations! Published in 2017 at "Science"
DOI: 10.1126/science.357.6356.1108-r
Abstract: Immunology The orphan receptor GPR15 mediates the trafficking of lymphocytes to the colon and skin and the recruitment of effector T cells to inflamed intestinal tissue. Using porcine colonic extracts, Suply et al. purified a… read more here.
Keywords: chemoattractant receptor; gpr15l; legitimizing chemoattractant; immunology ... See more keywords
Tyrosine sulfation and O-glycosylation of chemoattractant receptor GPR15 differentially regulate interaction with GPR15L.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of cell science"
DOI: 10.1242/jcs.247833
Abstract: GPR15 is a G protein-coupled receptor (GPCR) that directs lymphocyte homing to the colon and skin. Recent studies have identified a chemokine-like protein C10orf99/GPR15L as a functional ligand of GPR15. In this study we examined… read more here.
Keywords: gpr15l; sulfation; interaction; receptor ... See more keywords
C10orf99/GPR15L Regulates Proinflammatory Response of Keratinocytes and Barrier Formation of the Skin
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.825032
Abstract: The epidermis, outermost layer of the skin, forms a barrier and is involved in innate and adaptive immunity in an organism. Keratinocytes participate in all these three protective processes. However, a regulator of keratinocyte protective… read more here.
Keywords: skin; gpr15l; barrier formation; expression ... See more keywords