GPR37L1 controls maturation and organization of cortical astrocytes during development.
Sign Up to like & getrecommendations! Published in 2023 at "Glia"
DOI: 10.1002/glia.24375
Abstract: Astrocyte maturation is crucial to proper brain development and function. This maturation process includes the ramification of astrocytic morphology and the establishment of astrocytic domains. While this process has been well-studied, the mechanisms by which… read more here.
Keywords: cortical astrocytes; maturation; development; gpr37l1 ... See more keywords
GPR37L1 modulates seizure susceptibility: Evidence from mouse studies and analyses of a human GPR37L1 variant
Sign Up to like & getrecommendations! Published in 2017 at "Neurobiology of Disease"
DOI: 10.1016/j.nbd.2017.07.006
Abstract: Progressive myoclonus epilepsies (PMEs) are disorders characterized by myoclonic and generalized seizures with progressive neurological deterioration. While several genetic causes for PMEs have been identified, the underlying causes remain unknown for a substantial portion of… read more here.
Keywords: gpr37l1; seizure susceptibility; gpr37l1 variant; evidence ... See more keywords
Quantitative Proteomics Reveal an Altered Pattern of Protein Expression in Brain Tissue from Mice Lacking GPR37 and GPR37L1.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.9b00622
Abstract: GPR37 and GPR37L1 are glia-enriched GPCRs that have been implicated in several neurological and neurodegenerative diseases. To gain insight into the potential molecular mechanisms by which GPR37 and GPR37L1 regulate cellular physiology, proteomic analyses of… read more here.
Keywords: gpr37 gpr37l1; gpr37l1; brain tissue;
Abstract P2041: Wnt Signaling Regulates GPR37l1 Expression in Human Renal Proximal Tubule Cells
Sign Up to like & getrecommendations! Published in 2019 at "Hypertension"
DOI: 10.1161/hyp.74.suppl_1.p2041
Abstract: Aberrations in renal epithelial ion transport contribute to the pathogenesis of essential hypertension. G protein-coupled receptors (GPCRs) in the kidney regulate the reabsorption of essential nutrients, ions, and water from the glomerular filtrate. The functional… read more here.
Keywords: wnt signaling; renal proximal; proximal tubule; expression ... See more keywords