LY2405319, an analog of fibroblast growth factor 21 ameliorates α-smooth muscle actin production through inhibition of the succinate—G-protein couple receptor 91 (GPR91) pathway in mice
Sign Up to like & getrecommendations! Published in 2018 at "PLoS ONE"
DOI: 10.1371/journal.pone.0192146
Abstract: Fibroblast growth factor 21 (FGF21) is an important metabolic regulator expressed predominantly in the liver. In this study, we evaluated the role of LY2405319, an analogue of FGF21, in hepatic stellate cell (HSC) activation and… read more here.
Keywords: gpr91; production; liver; gpr91 pathway ... See more keywords
Increased succinate receptor GPR91 involved in the pathogenesis of Mooren's ulcer.
Sign Up to like & getrecommendations! Published in 2018 at "International journal of ophthalmology"
DOI: 10.18240/ijo.2018.11.01
Abstract: AIM To investigate the expression of succinate receptor GPR91 and its pathogenic roles in Mooren's ulcer (MU). METHODS Biopsy specimens were obtained from 7 patients with MU and 6 healthy donors. The expression of GPR91… read more here.
Keywords: receptor gpr91; gpr91; succinate receptor; mmp ... See more keywords