Depletion of Gprc5a Promotes Development of Diabetic Nephropathy.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the American Society of Nephrology : JASN"
DOI: 10.1681/asn.2017101135
Abstract: Background Renal glomeruli are the primary target of injury in diabetic nephropathy (DN), and the glomerular podocyte has a key role in disease progression.Methods To identify potential novel therapeutic targets for DN, we performed high-throughput… read more here.
Keywords: gprc5a; promotes development; depletion gprc5a; diabetic nephropathy ... See more keywords
Lung cancer suppressor gene GPRC5A mediates p53 activity in non‑small cell lung cancer cells in vitro.
Sign Up to like & getrecommendations! Published in 2017 at "Molecular medicine reports"
DOI: 10.3892/mmr.2017.7343
Abstract: Cellular tumor antigen p53 (p53) functions to maintain genomic stability and regulate cell apoptosis, while G protein‑coupled receptor class C group 5 member A (GPCR5A) is a lung cancer suppressor gene whose expression is induced by… read more here.
Keywords: p53; cell; gprc5a; lung cancer ... See more keywords