Platelet membrane lipid rafts protein composition varies following GPVI and CLEC-2 receptors activation.
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DOI: 10.1016/j.jprot.2019.01.014
Abstract: Lipid rafts are membrane microdomains that have been proposed to play an important role in several platelet-signalling cascades, including those mediated by the receptors Glycoprotein VI (GPVI), and C-type lectin domain family 1 member B… read more here.
Keywords: rafts protein; protein composition; gpvi clec; activation ... See more keywords
Significant Hypo-Responsiveness to GPVI and CLEC-2 Agonists in Pre-Term and Full-Term Neonatal Platelets and following Immune Thrombocytopenia
Sign Up to like & getrecommendations! Published in 2018 at "Thrombosis and Haemostasis"
DOI: 10.1055/s-0038-1646924
Abstract: Neonatal platelets are hypo-reactive to the tyrosine kinase-linked receptor agonist collagen. Here, we have investigated whether the hypo-responsiveness is related to altered levels of glycoprotein VI (GPVI) and integrin α2β1, or to defects in downstream… read more here.
Keywords: neonatal platelets; term; clec; gpvi clec ... See more keywords